Few Questions about Clen.

[Addictive]

I haven't really don't any research on SARMS so I want to get more knowledgeable about them.

I've read it's usually ran 2 weeks on, 2 weeks off. And some people use it after a cycle so they keep more of the gains.

Questions;
does it required any type of pct?
Is it damaging to the liver?
Is it recommended before or after cycle?

I'm not looking for a spoon feed, just some info.
I tried searching it, if there's any informative threads on clen I would He grateful if you post I'd love to read it.

[Vullfromsc]

clen does not need a pct
no damage to liver really (can damage kidneys if you get dehydrated, make sure you drink a lot of water)
recommended on cycle and during pct (anti-catabolic effects) but can be used at any time really

[POPS]

clen does not need a pct
no damage to liver really (can damage kidneys if you get dehydrated, make sure you drink a lot of water)
recommended on cycle and during pct (anti-catabolic effects) but can be used at any time really

exactly......ramp up your dose slowly, take taurine for cramps and have some benadryl on hand just in case.....

Depending on how lean you already are, a good diet and cardio regimine blows away clen anyday!!!

[Addictive]

exactly......ramp up your dose slowly, take taurine for cramps and have some benadryl on hand just in case.....

Depending on how lean you already are, a good diet and cardio regimine blows away clen anyday!!!

A good diet, cardio + clen = ...? Hah.
Thanks for all the info!

How long is it usually ran for? Or is it until you feel like stopping?

[POPS]

2 weeks on and 2 weeks off unless you take ketofin ( spelling??? ) then you can run it as long as you want, I think.....

[Vullfromsc]

here is how someone may run it (beginner doses):
Day 1: 20mcg
Day 2: 40mcg
Day 3: 60mcg
Day 4-11: 80mcg
Day 12: 60mcg
Day 13: 40mcg
Day 14: 20mcg

obviously, there are other ways to run it.. but usually it's 2 weeks on in a pyramid (like the one above or similar to the one above) then 2 weeks off and repeat

[Addictive]

Yea, I mean can you just repeat 2 weeks on, 2 weeks off For however long you want?
Sorry, didn't specified it.

Edit: vull is That for someone who's never ran clen? What if they ran aas/phs? Just wondering.

[Vullfromsc]

well i mean, for the first time use of clen i would probably recommend those doses. once you get used to taking it and know your body won't react poorly, you can get up to 150+mcg

[Addictive]

Ah, okay!
Yea I east reading other clen threads and saw way higher dosage but now I understand why it's that.

[sixoner]

there is absolutely no need to taper down the dosage on clenbuteral especially since continual use will result in Tachyphylaxis and the compound will begin to have diminishing results on its own.

ramp up your initial run to observe how you react to it and how you can tolerate its effect. for example 60, 80, 100, 120. you can repeat any of those dosages on the following day if you feel necessary to become accustomed to the effect 120mcg is probably as high as is necessary.
take a base body temperature reading for a few days prior to use that way you have something to go by as the clebuteral takes its effect and then you can monitor when its effect is beginning to diminish as well.
for maximum effect and to prevent the rapid desensitization of the beta-2 receptors that the clenbuteral selectively targets you can run ketotifen in conjuction with the clenbuteral. to keep the clenbuteral working optimally and for longer periods

from my experience benadryl does not work it does absolutely nothing in conjuction with clenbuteral with the exception of making you stupefied.

[Addictive]

What's tachyphylaxis?
Okay, go take normal dosage to observe how I react?
Id rather just run clen 2 weeks on, 2 weeks off so I'm not going into more stuff.
but I can repeat that For lets say, 4 months?

[POPS]

What's tachyphylaxis?
Okay, go take normal dosage to observe how I react?
Id rather just run clen 2 weeks on, 2 weeks off so I'm not going into more stuff.
but I can repeat that For lets say, 4 months?

I went 6 weeks following the 2 on and 2 off and had no issues. HOWEVER, I never ran past 100mcg/day....Also like stated above, no need to ramp down.

I ran it like this : 20/20/40/40/60/60/80/80/100/100/100/100/100/100. This way there was not a huge jump in sides.....but like I said, by the time I hit 80 I definately needed 3g of taurine and benadryl before bed.

If you get a " clen " cramp cause youre not taking taurine, I guarantee youll run to your local store to pick some up asap!!!!

[sixoner]

What's tachyphylaxis?

Tachyphylaxis is a medical term describing 'A rapid decrease in the response to a drug due to previous (long term) exposure to that drug'. Increasing the dose of the drug will not increase the pharmacological response. Tachyphylaxis may develop with an initial dose. This can sometimes be caused by depletion or marked reduction of the amount of neurotransmitter responsible for creating the drug's effect. Examples: Amphetamine, ephedrine (indirectly acting drugs)

Tachyphylaxis is a phenomenon which is characterized by the rate sensitivity: the response of the system depends on the rate with which a stimulus is presented. Specifically, a high intensity prolonged stimulus or often repeated stimulus may bring about a diminished response also known as desensitization.

In biological sciences, molecular interactions are the physical bases of the operation of the system. The control of the operation, generally, involves interaction of a stimulus molecule with a receptor / enzyme subsystem by, typically, binding to the macromolecule A and causing an activation or an inhibition of the subsystem by forming an activated form of the macromolecule B. Schematically,

p
A --------> B

Where p is the activation rate coefficient. Customarily, p is called a rate constant, but, since the p stands for measure of the intensity of the stimulus causing the activation, p may be variable (non-constant).

The above scheme is only the necessary condition for the rate sensitivity phenomenon and other pathways of deactivation of B may be considered, with the subsequent return to the inactive form of the receptor/enzyme A. Examples[1][2][3] offer particular use of such (mathematical) models in endocrinology, physiology and pharmacology.

thank you drive thru

the stimulus being clenbuteral the receptor being the bronchial beta-2 adrenergic receptors which it specifically targets for its effect. this is why it is absolutely unnecessary to taper down clenbuteral...its pointless youre already going to get a diminishing effect around 9-11 days of continual use without supplementing ketotifen. increasing the dose will not help..so decreasing the dose is surely not gonna do anything if youre going to taper down you may as well just discontinue use it would yield the same results

[Addictive]

Thank you for That phenomenal post onesixer. That Really help Me understand wbhat you were saying.
POPS I have that shit on hand now That you've said that. Hah and I always smoke before bed cause inhave insomnia so that'll help me sleep.

[sixoner]

right on bro...just remeber benadryl is kinda of a myth too...it has not been shown in any studies that I am aware of to re-sensitize or aid in recovery of the bronchial beta-2 receptors it does not work to keep clenbuteral working optimally or to prolong its use. I personally tried it and the results were exactly the same as if i took nothing in conjunction with clenbuteral.

ketotifen however works, and works well. from personal experience and research as well.

[Addictive]

I think I'm going to run it for the first bottle of just 2 weeks on, 2 off. And then try ketotifen another time.
I thought benadryl was for the headaches lol! I probably won't use any in conjunction with it.

Thanks for all the help!

[sixoner]

no problem..thats a reasonable protocol your receptors should have time to recover in 14days..from my experience around 9 days of considerable dosing you will begin to see diminishing effects/results if your diet and cardio and training are dialed in you will probably love the results...

let us know how it goes bro

[toothache]

Make sure to supplement potassium and taurine.

Clen depletes the liver of taurine. And potassium is needed for muscle cramps.

[sixoner]

absolutely I always forget to mention that tooth because I always take taurine anyway...but yeah I have heard of and seen a few bros fall out from cramping on clen I've never experienced any cramps personally possibly because of the taurine

[Addictive]

Thank the both of you! I'll get my bf% done, and maybe ill start a log and check bf after a few months.

[Rocksteady316]

sixoner -

im starting to believe your theory on the benadryl - i really enjoyed the comment of leaving one stupified...

i took some the other night just to fall asleep and i woke up the next day 10 hours later attempting to think what the hell i did last night... almost like if i went out got blacked out at a bar and somehow ended up home...

[sixoner]

yeah man that stuff skulldrags me too.. I had already used clen 2 previous times and had done a lot of research. I decided to run the diphenhydramine to sort of dispel the myth because for the life of me i could not find anything in tons of profiles, pharmacology, related studies anything at all that suggested it would aid in support of, or re-sensitization/recovery of the beta-2 adrenergic receptors...

sure enough besides straight up molly wopping my ass...it did nothing in regards to preventing tachyphylaxis caused by significant dosing of clen.

read a few profiles and pharmacology on benadryl and if you understand how clenbuteral works then its almost apparently clear that its just a bunk theory.

[mustgo69]

You guys seem to do your homewrok. I need advice/help. I am on day 6 of Clen at 100mcg. I am just trying to lose weight, I started at around 231 or so. I do a minimum of 30-40 minutes of cardio on the treadmill - usually 4 miles. I have tried 4 a day once a day then 2 1/2 miles twice a day and I have lost ZERO! I know its there, I got the shakes and drink plenty of water and take taurine for the cramps! I am going for the 2 weeks on and 2 off.

I will admit that my diet is not the best but I really don't eat that bad and figured that the Clen would really help out. What else can I do?

Sorry to Jack the thread,

[pskyle]

You guys seem to do your homewrok. I need advice/help. I am on day 6 of Clen at 100mcg. I am just trying to lose weight, I started at around 231 or so. I do a minimum of 30-40 minutes of cardio on the treadmill - usually 4 miles. I have tried 4 a day once a day then 2 1/2 miles twice a day and I have lost ZERO! I know its there, I got the shakes and drink plenty of water and take taurine for the cramps! I am going for the 2 weeks on and 2 off.

I will admit that my diet is not the best but I really don't eat that bad and figured that the Clen would really help out. What else can I do?

Sorry to Jack the thread,

Since you started at 231 lbs what are you at now? What was your bf % before? What type of cardio do you do? How often do you do cardio? Roughly what is your diet like?

[dec11]

Since you started at 231 lbs what are you at now? What was your bf % before? What type of cardio do you do? How often do you do cardio? Roughly what is your diet like?

do not listen to this stupid troll.

mustgo69, make your own thread for a better response