I think sometimes we get lost in our quest for the sweet spot and think that we can make hrt and exact science. When you look at how our bodies produce t, there is nothing exact about it. Time of day (and I think time of year), nutrition, rest, strength training, muscle mass, body fat and on and on.

I have become more diligent in varying my t injection days from 6 to 10. never going out of that span though. Same with Hcg and adex. Not promoting this at all for the noobs though. You have to be on for a long while before you know how the stuff you put in reacts and how your body deals with it. I think it takes the hypo male a good 5-6 months at least to get used to the new levels you obtain. With the half life of test c or e, I personally, really do not see the need to inject more than once every 6-10 days. I have seen no one on this board that has said it actually helped with e2 or acne or any other side by injecting twice a week with those hormones. Just my two cents.

I think another definition of sweet spot can be it is when we know our bodies well enough to choose the correct protocol for all the things we are putting in it. And to vary that protocol is working for me. I don't feel best on day three or four after injection when my levels are their highest, I feel best on the first few and the last few - but still pretty damn good in the couple of days in the middle.

But to each his own, and by all means after you really know your body, change things up a little - you might just find that sweet spot.