if it acts like estrogen at the pit gland, then it will slow LH production, lowering test production. Thats the agonist action.
tore doesnt have as much if any antagonist action at the pit gland. esp when compared to clomid. clomid has the antagonist action at the pit gland, which is the oppsite effect of the agonist aka estrogen.
and as was stated above, tamox was better at raising test levels than tore but they are both very mild in comparison in raise in T levels compared to clomid.
and if the arguement is that no direct study of LH levels were done between clomid and tore and tamox, then look at the end product. Tore and tamox increase GnRH sensitivity, clomid decreases it. Yet clomid has way larger increase in T levels with the GnRH desensivity.
Lem, I am 100% positive clomid acts like estrogen at pituitary, attaching to E receptors there. Basically, it competes with estrogen there, therefore blocking the neg feedback loop that E would create, and diminish gonadatropin. Because it acts like E there, E can not attach to receptors. Nolva does not do this. so in short, clomid does both and nolva is simply an anti-estrogen.
Last edited by THE-DET-OAK; 06-23-2011 at 05:30 PM.
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