First, tell your wife and explain why it is a good thing.
Second, if that avatar is not your wife, lose the avatar so you don't have to hide this forum from your wife.
Doing First and Second items will greatly reduce your anxiety issue!

If you are taking 0.55 mg of anastrozole 4 times a week, then you are probably taking too much. The sore nipples is confusing, though. Low E2 will make you feel like crap. Maybe you had sore nipples before starting the AI and now you are taking way too much AI?

FYI, controlling E2 is probably the hardes thing about HRT. It takes some work and has a learning curve.