Peptide Guru's (GET IN HERE)

[PK-V]

Huh!

However, unlike
GHRP-6, hexarelin does not induce food intake because of its incapability to drastically increase the grehlin
levels that are responsible for the feeling of hunger and faster emptying of the gastric system. But the
studies of Deghenghi et al. (1994) reported that hexarelinpossessed similar effectiveness in stimulating the
GH release in a long-lasting event and slightly more effective than the GHRP-6. These are supported by a
number of studies. Locatelli et al. (1999) reported that hexarelin provides protection and healing especially
for the cardiac dysfunction and abnormalities.

The most-studied Ghrelin mimetic peptides are GHRP-2, GHRP-6, hexarelin, and ipamorelin. Of these, ipamorelin is the least potent GH releasing compound but the compound that also has the least effect on cortisol and prolactin release. GHRP-6 is more potent with slightly more cortisol and prolactin release; GHRP-2 is more potent still; and hexarelin is the most potent of the four, with the most release of cortisol and prolactin as well. [3]

[3]Ghigo, E., Arvat, E., Muccioli, G. and Camanni, F. (1997) Growth hormone releasing peptides. Eur. J. Endocrinol. 136, 445–460



In relation to my DAC CJC I see no reason not to try it out especially in relation to my goal of modifying my body composition, if the HGH administration frequency vs effects studies are anything to go by

Consistent release fat loss vs Larger spike for an anabolic effect

It's CJC with the steroid equivalent of an ester, I can switch it up to CJC (non/DAC) when I get back to bulking for that der enhanced IGF-1 secretion post wo

Thanks for the input!

[M302_Imola]

Huh!

However, unlike
GHRP-6, hexarelin does not induce food intake because of its incapability to drastically increase the grehlin
levels that are responsible for the feeling of hunger and faster emptying of the gastric system. But the
studies of Deghenghi et al. (1994) reported that hexarelinpossessed similar effectiveness in stimulating the
GH release in a long-lasting event and slightly more effective than the GHRP-6. These are supported by a
number of studies. Locatelli et al. (1999) reported that hexarelin provides protection and healing especially
for the cardiac dysfunction and abnormalities.

The most-studied Ghrelin mimetic peptides are GHRP-2, GHRP-6, hexarelin, and ipamorelin. Of these, ipamorelin is the least potent GH releasing compound but the compound that also has the least effect on cortisol and prolactin release. GHRP-6 is more potent with slightly more cortisol and prolactin release; GHRP-2 is more potent still; and hexarelin is the most potent of the four, with the most release of cortisol and prolactin as well. [3]

[3]Ghigo, E., Arvat, E., Muccioli, G. and Camanni, F. (1997) Growth hormone releasing peptides. Eur. J. Endocrinol. 136, 445–460



In relation to my DAC CJC I see no reason not to try it out especially in relation to my goal of modifying my body composition, if the HGH administration frequency vs effects studies are anything to go by

Consistent release fat loss vs Larger spike for an anabolic effect

It's CJC with the steroid equivalent of an ester, I can switch it up to CJC (non/DAC) when I get back to bulking for that der enhanced IGF-1 secretion post wo

Thanks for the input!

ok you can copy and paste but do you truly understand the compounds you are about to put in your body? I suggest you stop by Dat's forum and do some more research on peptides. Yes GHRP-6 induces hunger in some so it wouldn't be the best for a cut but GHRP-2 releases more GH than GHRP-6 and doesn't have the hunger side effects. Hex to me is behind the times and there are far better choices. Also, your idea of CJC w/ DAC being a better fat burning choice is wrong. It's the large pulses of GH that help w/ fat burning and also have an anabolic effect. That steady stream that CJC DAC induces is going to lead to saturation and desensitivity.

[PK-V]

I copy and paste because it's the science yet you dispute it based on? broscience it seems

Elaborate on how hex is behind it's time! (im waiting)

Also your wrong again...



Researchers from the University of Michigan in Ann Arbor found that the mode of administration of growth hormonesupplements was important for achieving optimal effects. Continuous administration of GH caused the highest levels of IGF -1. Growth hormone exerts most of its anabolic effects by stimulating the production of IGF -1 in the liver and in tissues throughout the body. Administering GH several times during the day had the greatest effects on fat metabolism. Taking growth hormone once a day is best for maximizing its anabolic effects, while taking it several times a day is best for decreasing body fat. (Journal Clinical Endocrinology and Metabolism, 94: 2828-2834, 2009)

[M302_Imola]

I copy and paste because it's the science yet you dispute it based on? broscience it seems

Elaborate on how hex is behind it's time! (im waiting)

Also your wrong again...



Researchers from the University of Michigan in Ann Arbor found that the mode of administration of growth hormonesupplements was important for achieving optimal effects. Continuous administration of GH caused the highest levels of IGF -1. Growth hormone exerts most of its anabolic effects by stimulating the production of IGF -1 in the liver and in tissues throughout the body. Administering GH several times during the day had the greatest effects on fat metabolism. Taking growth hormone once a day is best for maximizing its anabolic effects, while taking it several times a day is best for decreasing body fat. (Journal Clinical Endocrinology and Metabolism, 94: 2828-2834, 2009)

Here is a post written by DATBTRUE on GHRP's, you will see that Hex isn't the greatest choice:

GHRP-6 at the saturation dose 100mcg does not really increase prolactin & cortisol but may do so slightly at higher doses. This rise is still within the normal range.

GHRP-2 is a little more efficacious then GHRP-6 at causing GH release but at the saturation dose or higher may produce a slight to moderate increase in prolactin & cortisol. This rise is still within the normal range although doses of 200 - 400mcg might make it the high end of the normal range.

Hexarelin is the most efficacious of all of the GHRPs at causing an increase in GH release. However it has the highest potential to also increase cortisol & prolactin. This rise will occur even at the 100mcg saturation dose. This rise will reach the higher levels of what is defined as normal.
Desensitization

GHRP-6 can be used at saturation dose (100mcg) three or four times a day without risk of desensitization.

GHRP-2 probably at saturation dose several times a day will not result in desensitization.

Hexarelin has been shown to bring about desensitization but in a long-term study the pituitary recovered its sensitivity so that there was not long-term loss of sensitivity at saturation dose. However dosing Hexarelin even at 100mcg three times a day will likely lead to some down regulation within 14 days.

Notice in the article you posted it states "Administering GH several times during the day had the greatest effects on fat metabolism. Taking growth hormone once a day is best for maximizing its anabolic effects, while taking it several times a day is best for decreasing body fat". Notice it says taking GH several times a day is best for decreasing body fat...now are you confusing several w/ continuous? Several means multiple doses throughout the day...continuous means a constant GH release which DAC would give you. Also, the author confuses me by using GH in a lot of places where he should be using peptides. I'm confused if he wrote this pertaining to synthetic GH or endogenous GH pulsed from peptides.