Well, although dboll has been structurally altered at the 17th carbon position to allow it to survive ingestion so it may be absorbed into the blood after its first pass through the liver it still breaks down by a % depending on the grade of product made. So based on his question as to eat or not to eat when taking the pill itself, my arguement/opinion would be to take it with a high lipid food which should help shuttle the 17 Alpha-Alkylated through/into the cell membranes allowing for a higher % yield first pass thus better absorption into the blood after first pass.