Crisler is looking at things from both sides of the fence.
One: How can I keep a man on a weekly protocol that he will benefit from and stick with and that is not complicated considering life style. Thus, hCG two and one day before Test injection followed by AI...simple.
Two: The best protocols are where we can mimic our body's own rhythms. If a man was willing to take small doses of Test, hCG and AI everyday it would be ideal! But in the real world (for most, not all) it's just impractical. So the compromise is Crisler's protocol which seems to stick with a lot of men.
For diligent guys like me, I can go more granular and almost go day to day.
Need to think of the masses when you are a Physician.
Although I agree with what gd said, I was just thinking in terms of the hormones:
Crisler's idea is to avoid "over peaking" the T levels by timing the HCG better.
First, I'm not convinced this is necessarily bad - the sublingual studies show T peaks over 2000 ng/dL with good effects.
Second, the half-life of HCG is something around 30-48 hours depending on who you believe (the studies are all over the place) so there's no need to space the injections so closely together.
Not that I advocate high doses of HCG, but his claim that it causes "Leydig cell desentization to LH" is not true.
Obviously, he is the experienced Dr. and I might know jack, but I think there's room for other opinions.
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