
Originally Posted by
ecdysone
Where I used to work, the nursing students were taught not to massage SQ injections because it might force the drug into the cutaneous layer (from the underlying fat) and alter its absorption. Often this increases the absorption rate which, depending on the substance administered, might/might not be an important consideration. I know insulin patients are usually told not to massage or squeeze the injection site for this reason.
I'd have to think about the consequence of increasing the absorption of HCG and whether forcing it into the cutaneous layer is a good or bad concept.