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Thread: Why not low dose clomiphene instead of HCG on TRT?

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  1. #1
    Join Date
    Apr 2012
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    Montreal Canada
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    basicaly the way i see it - clomid can be used if you have secondary hypogonadism - i think the question is wether long term use is safe, i know on a blog by a male health doctor that clomid is recomended over HCG if the pituatry is working as its less cumbersome etc...

    http://www.maledoc.com/blog/2010/04/...ge-5/#comments

    i subscribe to that line of thinking- if you have a functioning pituatry- why not excersise it? im not convinced shutting down pituatry function is a good option- something about that doesnt sit right with me.

    also men taking clomid experience low libido and become emotional experience gyno - all are symptoms of high estrogen ( from aromatase conversion) i would suggest taking an AI temporarily alongside the clomid when these sides develop temporarily ( few days).

    clomid increases test and also increases estrogen (thru aromatase conversion) which is free to bind- good if its in the right ratio- if it gets out of ratio eg too much estrogen,thats when the sides flare up , an AI which prevents the estrogen from being manufactured and thereby binding with the estrogen receptors in your manboobs may be a good idea.

    its a fine balancing act- dont forget about the rebound effect if clomid is stopped. a taper off clomid or Dosing on an AI at the end of a clomid cycle is a good way of preventing sides.

    does anyone else agree with my thinking>?
    Last edited by Simon1972; 06-25-2012 at 10:44 PM.

  2. #2
    Join Date
    May 2012
    Posts
    284
    Quote Originally Posted by Simon1972 View Post
    i subscribe to that line of thinking- if you have a functioning pituatry- why not excersise it? im not convinced shutting down pituatry function is a good option- something about that doesnt sit right with me.

    also men taking clomid experience low libido and become emotional experience gyno - all are symptoms of high estrogen ( from aromatase conversion) i would suggest taking an AI temporarily alongside the clomid when these sides develop temporarily ( few days).

    clomid increases test and also increases estrogen (thru aromatase conversion) which is free to bind- good if its in the right ratio- if it gets out of ratio eg too much estrogen,thats when the sides flare up , an AI which prevents the estrogen from being manufactured and thereby binding with the estrogen receptors in your manboobs may be a good idea.
    From what I can tell, the side effects are mostly completely dose related. With the low doses I`ve seen in studies on clomiphene monotherapy, no side-effects were reported. I did not experience any side-effects either.

    Most of them seemed to restore enhance sexual function on clomiphene as well, but reading about the experience of others, loss of libido seems to be a common experience.

    Regards,

    Renholder

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