hCG and Pregnenolone; What you should know.

[steroid.com 1]

Does HCG automatically equate to higher E2 levels?

It can, but generally seen in higher doses like >500iu daily. There should be no need to dose greater then 350iu daily. This is one peptide where smaller doses more frequently is better. When E2 is elevated it can do so in the testes where an AI is largely ineffective in controlling. If you were diagnosed as Secondary Hypogonadal you will most likely see an increase in natural production...which is a good thing

Back filling the pathways is always a good thing for many reasons. If you don't go with a transdermal cream look for micronized pills; 25mg of each twice daily will do the trick!

[gbrice75]

Does HCG automatically equate to higher E2 levels?

It can, but generally seen in higher doses like >500iu daily. There should be no need to dose greater then 350iu daily. This is one peptide where smaller doses more frequently is better. When E2 is elevated it can do so in the testes where an AI is largely ineffective in controlling. If you were diagnosed as Secondary Hypogonadal you will most likely see an increase in natural production...which is a good thing

Back filling the pathways is always a good thing for many reasons. If you don't go with a transdermal cream look for micronized pills; 25mg of each twice daily will do the trick!

Thanks for the fast reply.

I was prescribed 500iu 2x weekly. Not certain at this point whether I should stick with that or bump the frequency while lowering the dosage to around 350iu EOD-ish.

Re: back filling - I saw your recommendation for lef dot org and am looking into both aforementioned supplements now. As well, I just picked up Vitamin D (2000iu per softgel although I'm uncertain as to reasonable dosage) and am looking into Stinging Nettles; the latter 2 in an effort to lower my SHBG.

Would love it if you visited my thread. Don't mind me, i'm a shameless self promoting whore.

[jm100]

Does HCG automatically equate to higher E2 levels?

It can, but generally seen in higher doses like >500iu daily. There should be no need to dose greater then 350iu daily. This is one peptide where smaller doses more frequently is better. When E2 is elevated it can do so in the testes where an AI is largely ineffective in controlling. If you were diagnosed as Secondary Hypogonadal you will most likely see an increase in natural production...which is a good thing

Back filling the pathways is always a good thing for many reasons. If you don't go with a transdermal cream look for micronized pills; 25mg of each twice daily will do the trick!

I was wondering about this! I know I've heard of some people complaining that hCG made them look 'soft' or retain water from the increased E2 levels, but I hadn't thought about the high doses and/or frequency (and looking soft and/or bloated doesn't sound like a very fun way to live if you're going to be taking it long term along with TRT, so I've been hesitant to add it, but if it tends to happen mostly just at higher doses that makes me less hesitant about it).
This is a great sticky! Very informative.

[rmarganti]

Just stumbled on this forum. My estradiol levels actually went down after monotherapy with HCG? Let me give you a little background and the lab results and maybe you can shed a little light on the subject for me. I had been experiencing symptoms of low T last year (low libido, erections not as hard as they used to be, poor sleep, low energy, poor recovery from workouts etc.) so I decided to have some bloodwork done. I am a 51 year old male, 5'-09", 190 lbs. On 12/19/12 the results of my labs were Total Test-552ng-dL, LH-6.1 mIU/mL, FSH-4.1-mIU/mL, Estradiol-23.6 pg/mL. In January I went to see my family doctor and described my symptoms to him. He had me do another lab to test Free T which came back at 10. All other hormones: cortisol, thyroid, etc. were in the mormal range so he didn't think any therapy was indicated. All the research I've done reccomends free T levels be in the 19-25 range, so I disagreed with his evaluation. After doing a little reading I came upon a book by Eugene Shippen who had success treating low T with HCG monotherapy, so I purchased some on the Internet. Shippen reccomended 400 iu daily for 5 consecutive days and 2 days off. After 3 weeks he reccomended blood work to see how the patient was responding. I did some research on the Internet and decided to use 200 i.u. per day, 7 days a week instead. On 2/1/13 my blood work results were Total Test-634, LH-1.1, FSH-1.9 and Estradiol-21.4. My free test went up approx. 15% and my Estradiol level actually went down 2 points? The HCG improved my mood significantly and libido a little, however my energy levels, recovery were not. I picked up some injectable B complex and Super MIC about a month ago and have been using it regularly. My energy has improved and my love handles have almost vanished. I would still like to get better sleep and up my libido though, so I have made an appointment with a different doctor to try adding some injectable Test cyp or enanthate to my therapy. I continue to take the HCG at 200 iu daily while waiting for my doctor's appointment, but am unsure how to adjust my HCG dose if I decide to add the Test. Your forumn has been a source of great info. for me. Any suggestions or advice would be greatly appreciated.