My Doc states he does see elevated BP in some men once on TRT, especially if they are big guys to begin with. I've been on BP medicine for years, but mostly to control Migraine Headaches. Since starting TRT almost 3 years my BP has gone up somewhat but is controlled with Atacand & Amlodipine. My BP goes up significantly when I take NSAIDs like Aleve or Advil for extended periods. I'm on a large daily dose of Aleve right now for a shoulder injury and my BP has risen to 140/90 on some days. I usually run about 130/75.