My first cycle while I had an issue to where all my shit was in my backpack and it got stolen and after a few days my nips started getting tender and instead of doing blood work and doing the right thing all I could get was adex at the time and so I was taking like .5ed and my estrogen got too low and I couldn't get an erection and my joints started hurting. Dropped the ai to .5 every other day and my boner came back and joints stopped hurting.Originally Posted by Chx beach 79