It can stimulate big differences.
A man who is otherwise healthy will produce LH in very low pulsitative doses as needed throughout the day to regulate androgen serum levels.
When a man is Secondary Hypogonadal and has to introduce HCG to stimulate the testes to function properly when on a TRT protocol he will never be able to achieve the same balance that he operates at physiologically. In other words, LH is produced when needed as need in very small doses thought the course of a mans day.
Typically, we inject HCG two, three or four times a week for the most part in much larger doses at point of injection than the healthy body would ever produce at one given time...we can't replicate the biological processes.
So, if a man injects 3000iu of HCG a week for 18 weeks that would be far more than the healthy body would ever need and the resulting increase in intratesticular E2 as a byproduct.





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