No, not really. Tadalafil isn't like Bremelanotide (pt-141) which is designed to enhance libido through CNS activation. Cialis works by increasing the availability of nitric oxide from nerve terminals and endothelial cells, which stimulates the synthesis of cGMP in smooth muscle cells. Increased cGMP relaxes smooth muscle and enhances blood flow to the corpus cavernosum of the penis allowing for better engorgement to promote firmer erections. At 5-10mg the effect mostly occurs during "stimulation" as opposed to randomly.Originally Posted by Knockout_Power
Anecdotally I feel as though the increased NO and endothelial elasticity causes better pumps during work outs but Im not walking around with a stiffy while I lift.