Week 8 of my 12 week cycle of TestE 600mg/wk and I have done nothing but quads except for 1 injection in the galute on week 2. I have pretty muscular quads so that isn't an issue. Literally no soreness the next day at the point and i inject 2ml at a time (1ml test, 1ml b12). When I say I, i mean my wife. Because for whatever reason i can't put the needle in myself lol(well i can it just takes me 30+ mins of psyching myself out to do it) but once it is in I can inject no problem.