You continue to answer your own question to a degree. You keep saying "obvious sides". The sides I would concern myself with would be more of the (less noticeable) sides like Sgt. mentioned. To answer your question, yes. You want to keep estrogen in the normal ranges on or off test. Individual responses are different to low or high end of that range. Some prefer to keep their estrogen on the high end of the normal spectrum and calim they feel better when doing so.

I would ask you to not question why an AI is neccessary but answer why one would NOT include it.