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  1. #1
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    Quote Originally Posted by MuscleInk View Post

    I've self-medicated a range of doses from .25 to 3mg (my own N=1 dose escalation P1 trial, lol). Sub-1mg dose didn't have any discernible effects. 3mg was a bit intolerable due to nausea (no emesis) and skin flushing was more pronounced. 2mg produced similar libido effects as with 3mg but without nausea.

    I've noticed skin hyperpigmentation/darkening since I've been using pt-141 on a regular basis (anywhere bw a few times a month to a few times per week). I attributed the skin changes to the pt-141 as it's closely related to melanotan II. Anyone else experiencing this or have thoughts on this? MI, what's your take?

  2. #2
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    marcus300 is offline ~Retired~ AR-Platinum Elite-Hall of Famer ~
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    Quote Originally Posted by AnabolicDoc View Post
    I've noticed skin hyperpigmentation/darkening since I've been using pt-141 on a regular basis (anywhere bw a few times a month to a few times per week). I attributed the skin changes to the pt-141 as it's closely related to melanotan II. Anyone else experiencing this or have thoughts on this? MI, what's your take?
    I was told the tanning agent is taken out of the PT141 and not heard anyone having these side, maybe you have MELANOTAN II

  3. #3
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    Quote Originally Posted by AnabolicDoc

    I've noticed skin hyperpigmentation/darkening since I've been using pt-141 on a regular basis (anywhere bw a few times a month to a few times per week). I attributed the skin changes to the pt-141 as it's closely related to melanotan II. Anyone else experiencing this or have thoughts on this? MI, what's your take?
    I haven't observed that effect - but I've only dosed three times and usually about 3 weeks apart. Any compound that mimicks or stimulates MSH production could cause a change in pigmentation (as you are well aware). There is also a correlation between estrogens, MSH and hyperpigmentation which has left me wondering if anabolic users may see some hyperpigmentation if E levels weren't kept in check.

    I've read conflicting reports about whether Bremelanotide/PT-141 will cause changes in pigmentation (and that was its original intended application) or if its been modified solely for libido enhancing effects.

    Maybe I should increase my dose frequency? Then I could avoid the sunless tanning sprays guys use for BB shows and get the added benefit of libido enhancement (I'm sure my wife will be thrilled at that prospect!)

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