No...in most cases the HPTA is fully developed during by the late teens I men. My concern would be less about the individual glands and more about the over all system development. The endocrine system works directly with the nervous system and releases hormones that effect every cell in the body. Excess levels of hormones such as estrogen and testosterone in the human body can have an adverse effect on the overall system.
For 1 huge example: GROWTH can be effected when increased levels of test are introduced into the system causing skeletal maturation.
Endocrine regulation of longitudinal bone growth. [Endocr Dev. 2011] - PubMed - NCBI
Again..it's best to look at the entire system as well as how it relates to the other systems in the body, instead of just looking at the HPTA alone.





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