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Thread: Estrogen, Prolactin, Progesterone Management + Gynecomastia Prevention & Reversal

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  1. #1
    austinite's Avatar
    austinite is offline HRT Specialist ~ AR-Platinum Elite-Hall of Famer ~
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    Quote Originally Posted by cgi View Post
    Definetely not useless. I understand what you were trying to get across. I guess I'm just not as educated in hormone science. People often say that Tren and Deca are "progesterones" meaning they up your progesterone. As far as Prolactin is concerned are they also a prolactin increaser or is the prolactin increase a result of progesterone. Can a compound up prolactin without upping progesterone and vice versa or are they 2 totally seperate and unrelated hormones. These are the things I guess I need to know.
    Prolactin and Progesterone are 2 different hormones. Yes, it is possible that one could be elevated and the other not.

    Tren and deca are Progestins. Progestins stimulate your progesterone receptors and result in higher production. Progesterone comes originally from cholesterol, which is converted to pregnenolone, and then progesterone. But it's also produced from adrenal gland and testes.

    Prolactin on the other hand, comes from the pituitary. This is a gland in your brain that releases growth hormone, prolactin, oxytocin and others. Pituitary also signals other glands to release hormones as well. 19-Nor steroids like Tren and deca, upregulate prolactin receptors. This results in more production. We use dopamine agonists because dopamine binds to receptors and blocks prolactin secretion.

    Hope that clears it up some.
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  2. #2
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    Quote Originally Posted by austinite View Post
    Prolactin and Progesterone are 2 different hormones. Yes, it is possible that one could be elevated and the other not.

    Tren and deca are Progestins. Progestins stimulate your progesterone receptors and result in higher production. Progesterone comes originally from cholesterol, which is converted to pregnenolone, and then progesterone. But it's also produced from adrenal gland and testes.

    Prolactin on the other hand, comes from the pituitary. This is a gland in your brain that releases growth hormone, prolactin, oxytocin and others. Pituitary also signals other glands to release hormones as well. 19-Nor steroids like Tren and deca, upregulate prolactin receptors. This results in more production. We use dopamine agonists because dopamine binds to receptors and blocks prolactin secretion.

    Hope that clears it up some.
    Thanks. Also serious questions. due to the dopamine thing does that mean that (edit: taking medical substances that stimulate dopamine will result in blocking prolacting?)
    Last edited by cgi; 08-10-2013 at 10:18 PM.

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