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Thread: How long to metabolize estrogen ??

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    How long to metabolize estrogen ??

    Hey guys,

    For some reason I did not react to aramosin. My e2 levels were sky high (450 pmol/l) even on 50mg of aramosin a day. I'm using 750 mg test e pw.

    Ive moved over to Arimadex. How long will it take my estrogen that's already floating around my system to be metabolized ?

    Does it usually take a couple days or a couple weeks???

    Thanks...
    Last edited by athletic.guy; 11-10-2013 at 02:43 AM.

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    I've been searching the net for the last couple hours and can't find an answer.

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    Was it pharma grade aromasin or ugl ?

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    Quote Originally Posted by clarky. View Post
    Was it pharma grade aromasin or ugl ?
    It's was generic pharma grade Exemestane. I tried a few different brands. It just doesn't work on me. I'm one of the unlucky ones.
    Last edited by athletic.guy; 11-10-2013 at 05:29 AM.

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    You sure are mate but we are all different it should only take a few days to a wk to settle down how much are you taking

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    Quote Originally Posted by clarky. View Post
    You sure are mate but we are all different it should only take a few days to a wk to settle down how much are you taking
    I started 1mg Arimadex ed for 3 days and now using 0.5mg eod and planning on a blood test tomorrow.

    Its been a week since starting the Adex.

    Btw, my e2 was at 380 pmol/l @ 25mg ed so that's when I jumped up to 50 mg ed (and threw in 20mg tamaxofin to be safe) and a week later I was at 450. I immediately started Adex.
    Last edited by athletic.guy; 11-10-2013 at 05:47 AM.

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    Any VET's like to comment on the topic??

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    E2 spikes only seem to last about 2 days. This will vary by individual depending on e2 levels and metabolism.

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    Quote Originally Posted by athletic.guy View Post
    I started 1mg Arimadex ed for 3 days and now using 0.5mg eod and planning on a blood test tomorrow.

    Its been a week since starting the Adex.

    Btw, my e2 was at 380 pmol/l @ 25mg ed so that's when I jumped up to 50 mg ed (and threw in 20mg tamaxofin to be safe) and a week later I was at 450. I immediately started Adex.
    I have a comment on this but need to look into a few things before I post. I will get back to this thread.

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    Quote Originally Posted by jimmyinkedup View Post
    I have a comment on this but need to look into a few things before I post. I will get back to this thread.
    Would love to hear more comments on this. But just to make things more complicated my e2 skyrocketed big time when changing over to ADEX and adding nolvadex.

    So my conclusion is the aramosin was working, my body just converts allot into e2. I will continue the ADEX at 1mg ed and stop all my test shots until further blood test put my e2 back into a normal range.

    So the question is....... Why do I convert so much test to estrogen ???? Anyone???

    OR COULD IT BE I EAT 2LBS OF ESTROGEN FILLED CHICKEN PER DAY ???
    Will hormone free chicken really make a difference guys?
    Last edited by athletic.guy; 11-13-2013 at 06:36 AM.

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    What were your previous cycle experiences?

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    I strongly suggest you do not over-do the adex initially or you'll find yourself quickly crushing your E and struggling once again. Slow and steady adjustments are the best course to follow then re-test in a month.
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    Quote Originally Posted by kelkel View Post
    I strongly suggest you do not over-do the adex initially or you'll find yourself quickly crushing your E and struggling once again. Slow and steady adjustments are the best course to follow then re-test in a month.
    I'm re testing every week. My e2 levels have never been this high. And neither have my doses of AI.

    Like I said I was on 1 mg ed for 3 days then 1 mg eod and my e2 skyrocketed over double the 450 which I was on 50mg aramosin a day.

    My cycle only had 750 mg test week which I stopped a week ago now.

    Could the hormone filled chicken play a part in it? I eat 2 lbs a day of it....

    Before anyone says it both AI's are genuine shit pharma grade. That's not the problem.

    Anyways I'm actually trying to crush my e2 just to be safe because I would rather wy e2 be below 20 than continue above 1000 pmol/l
    Last edited by athletic.guy; 11-13-2013 at 01:08 PM.

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    I wonder if the nolva is throwing off e2 #'s .... (thats what i need to look into)

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    remember adex does bot reduce estrogen, it only blocks it from converting, so you have to wait until your body uses what's in your blood stream while AI is blocking new estrogen production. like Kel said go easy on the AI, its working in the background.

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    Quote Originally Posted by jimmyinkedup View Post
    I wonder if the nolva is throwing off e2 #'s .... (thats what i need to look into)
    Changes in serum estrogen levels in women during t... [Am J Surg. 1997] - PubMed - NCBI
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    How about that..I thought it could be...how much is the ?

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    Very interesting. I only started on the nolvadex when blood results shown e2 dangerously high. I only used it for a week to prevent gyno.

    It's been a week on just 1mg Ed of Adex and no test e. blood test again tomorrow. Hopefully we can get it under control.

    But in relation to the nolvadex, that could of played a part in the e2 levels shooting up over 1000 pmol/l. That e2 test was done 4-5 day after adding nolvadex into my mix, and after adding nolvadex to 1mg Adex eod my e2 levels over doubled !!

    But now I'm on just the 1 mg adex ed. Fingers crossed i can get it under control ASAP.
    Last edited by athletic.guy; 11-13-2013 at 04:45 PM.

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    You need consistency to get stable. You can't be consistent on 1mg adex eod as you'll crash. That has to be short term only then pick what you feel is your maintenance dose, be consistent on that for several weeks (3-4) then retest.
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    Quote Originally Posted by kelkel View Post
    You need consistency to get stable. You can't be consistent on 1mg adex eod as you'll crash. That has to be short term only then pick what you feel is your maintenance dose, be consistent on that for several weeks (3-4) then retest.

    I consistently took 50 mg ed of aromasin for 4 weeks. But my levels were triple the optimum range. I think it's safe to assume my body converts high amounts of test E to e2 and needs either a higher dose or aromasin or the equilivent dose of Adex. So I'm asking 75mg aramosin Ed should be close to 1mg Adex eod.

    But only blood work will tell 4 sure. Ill continue till I get it perfect....

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    Quote Originally Posted by bass View Post
    remember adex does bot reduce estrogen, it only blocks it from converting, so you have to wait until your body uses what's in your blood stream while AI is blocking new estrogen production. like Kel said go easy on the AI, its working in the background.
    I realize this. That was the heading in this topic. How long does it take to metabolize what's already In my system. It defiantly isn't a couple days with me. As I said Changed to a large dose of Adex AND added nolvadex and my e2 levels doubled in 5 days....

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    Could the use of nolvadex slow down the metabolism of e2 in my system?

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    Nolva lowers plasma levels of adex by 20-30% by competing for metabolism by the same enzyme. Not a huge deal, though.

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    Quote Originally Posted by Bonaparte View Post
    Nolva lowers plasma levels of adex by 20-30% by competing for metabolism by the same enzyme. Not a huge deal, though.
    Can you translate that into simple English please?

    Does nolvadex do the same to Aramosin?

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    ...Nolva lowers adex levels by 20-30%.

    No, but aromasin isn't nearly as potent as Adex, and you've already wasted your time and money with that one.

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    Quote Originally Posted by Bonaparte View Post
    ...Nolva lowers adex levels by 20-30%.

    No, but aromasin isn't nearly as potent as Adex, and you've already wasted your time and money with that one.

    Just curious if nolvadex does the same to letro?

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    Quote Originally Posted by athletic.guy View Post
    Just curious if nolvadex does the same to letro?
    It does. But that's not a huge deal, because you can always just take 30% more AI.

  28. #28
    Quote Originally Posted by athletic.guy View Post
    Hey guys,

    For some reason I did not react to aramosin. My e2 levels were sky high (450 pmol/l) even on 50mg of aramosin a day. I'm using 750 mg test e pw.

    Ive moved over to Arimadex. How long will it take my estrogen that's already floating around my system to be metabolized ?

    Does it usually take a couple days or a couple weeks???

    Thanks...
    i dont see how thats possible if you legit aromasin. arimidex should lower estrogen levels almost by 50% after first use. if you use arimidex you should be fine fairly soon. everyone converts estrogen at different rates. but one thing is true if you have higher fat content especially in belly you will convert much more estrogen then someone who lean

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    Quote Originally Posted by Ctits23 View Post
    i dont see how thats possible if you legit aromasin. arimidex should lower estrogen levels almost by 50% after first use. if you use arimidex you should be fine fairly soon. everyone converts estrogen at different rates. but one thing is true if you have higher fat content especially in belly you will convert much more estrogen then someone who lean
    I'm currently 225 lbs @ 12%

    AI won't do anything about estrogen that is already in my system. What's done is done. Now it's up to the body to get rid of it. But if I continue to get higher estrogen after stopping my test e shots and I'm continue at 1mg arimadex ed then I'm in deep shit and ill go see Dr ENDO.

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