
Originally Posted by
Bonaparte
MI, that was your layman's explanation? Lol
Let me try: injecting allows the drug to reach the bloodstream directly. Ingested (oral) drugs need to pass through the liver a first time before reaching the bloodstream. So by injecting a substance, you avoid the first pass through the liver, but it will still pass through the liver a few times later.
So yes, injecting drol reduces toxicity and/or allows for lower doses, since you don't lose any to the liver before ever reaching the bloodstream.