I ran a batch of test E that every time I pinned would leave the site swole and swore for about a week. Sometimes worse then others. Antibiotics didn't help. It was not infected. It was just a bad reaction to the gear or something in it. IBP and massaging it hard (This hurt bad) helped. Also benadryl might help if your reacting to something in the gear.
I switched to Test C and have not had a problem sense.