Amount of time for new BW After starting AI

[Docd187123]

It lowers total estrogens by that much not estradiol. The biggest decrease is in estrone and estrone metabolites I believe not estradiol which is what we're usually concerned with.

[2Sox]

It lowers total estrogens by that much not estradiol. The biggest decrease is in estrone and estrone metabolites I believe not estradiol which is what we're usually concerned with.

Please expand on this. So does that mean we shouldn't be pleased with the results of estrogen reduction describe above? Can you clarify? Again, I'm really asking?

Maybe we should go back to the original article referenced in the other thread to see what was really meant?

[2Sox]

I'm not sure the differentiation is a concern. Since the action of exemestane destroys the aromatase enzyme itself, by the very action of the drug (reducing aromatization) serum estradiol (estrogen) is reduced. This is what we want.