I'm not doing a 5x5 currently but have in the past. You're point is accurate though, right now I'm experimenting with seeing how far I can take LP with anabolics. One way of orogramming is a volume day, intensity day, and recovery day but you're still training the lift, the body part, the CNS, etc multiple times per week.
There are other more sadistic methods out there also. Look at the success of Oly lifters, GVT, Bulgarian training, Sheiko, etc and how many of them squat up to 6-7days per week and sometimes they squat multiple times per day. It's all about accommodating the workload, increasing conditioning, etc.
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