Quote Originally Posted by CobraMustangSVT View Post
Hi,
Do you know what causes the transdermal fatigue? I was reading that it's thyroid issues that causes thickening of the skin, which leads to poor absorption.
If that were the case, then more men would have thyroid issues. Most men, the majority, will find transdermals lose at least some level of their effectiveness overtime, how much and how soon is what varies.