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Thread: Intra-testicular aromatizing... if this is true, then why does no one talk about this

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  1. #1
    Join Date
    Aug 2009
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    13,506
    1) that wouldn't matter on cycle (when estrogen is a much larger concern), because your testes aren't producing test anyway.
    2) AIs affect the aromatase enzymes in your testicles as well (because, you know, they're supplied with blood circulating through your body).
    3) No AI can directly reduce circulating estrogen. But existing estrogen is metabolized within a few days.

  2. #2
    Join Date
    May 2014
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    4,109
    Testicular estrogen is synthesized by the leydig and the germ cells and is essential for fertility.

    Quote Originally Posted by Bonaparte View Post
    1) that wouldn't matter on cycle (when estrogen is a much larger concern), because your testes aren't producing test anyway.
    I agree that it doesn't matter. However, if one is on cycle and taking HCG won't the testes continue producing test?

  3. #3
    Quote Originally Posted by Bonaparte View Post
    1) that wouldn't matter on cycle (when estrogen is a much larger concern), because your testes aren't producing test anyway.
    Ok, thanks for that info. Please note though, I'm not "on cycle," but am on trt, specifically Clomid. (also why I posted in this sub-forum) While raising my T, it also shot my E2 up to 80 (max range was 42). I'm now trying research chemicals Arimidex and/or Aromosin (as well as reducing Clomid -- the reason I'm being so aggressive, I have to 'peak' for 'event' in a few weeks; want max normal T and low E2 before then, maintain lean tissue and 'dry out' abs). I have a trt doc, but the research chemicals are cheaper than scripts, and at least the Clomid seemed to work, so I'll use them for now.

    Quote Originally Posted by Bonaparte View Post
    2) AIs affect the aromatase enzymes in your testicles as well (because, you know, they're supplied with blood circulating through your body).
    The person speaking of the intra-testicular aromatization, said something about the AI's couldn't compete w/ the receptors / enzymes, whatever, in the testes. The AI's were outnumbered 100:1 in the testes. But I hope you're right -- good to know!

    Quote Originally Posted by Bonaparte View Post
    3) No AI can directly reduce circulating estrogen. But existing estrogen is metabolized within a few days.
    Good -- that's another question I had -- how long does it take to 'clear' E2 from one's system. Only a few days? Awesome!

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