Doc prescribed A LOT, what to do....?

[FakeLove]

If you're not using exogenous testosterone and your LH is still in the game, Adex actually might not crash the E2. Correct me if I'm wrong, but all the studies I'm able to find of Anastrozole in males, are done on a normal males with elevated E2. Doses have been 0,5mg or 1mg daily. In those studies it seem to decrease E2 around 50% regardless of the dose. So it significantly lowered their E2, but didn't crash. Unlike it does when on gear. I'm not sure if I'm able to post any links, but the studies are quite easy to find. Anyway, just something to think of.

[Keep_It_Moving]

If you're not using exogenous testosterone and your LH is still in the game, Adex actually might not crash the E2. Correct me if I'm wrong, but all the studies I'm able to find of Anastrozole in males, are done on a normal males with elevated E2. Doses have been 0,5mg or 1mg daily. In those studies it seem to decrease E2 around 50% regardless of the dose. So it significantly lowered their E2, but didn't crash. Unlike it does when on gear. I'm not sure if I'm able to post any links, but the studies are quite easy to find. Anyway, just something to think of.

Once I go on the AI, gotta stay on it correct and play the balancing game....?

[OingoBoingo]

Once I go on the AI, gotta stay on it correct and play the balancing game....?

Not necessarily. In six months I've gone from taking Anastrozole every 6 days, to every 8 days. It could be that as our body gets used to having Testosterone again, the need for an AI might go away.

But I'm also thinking that we as a group are taking more Testosterone than we really need to.

[Keep_It_Moving]

Just want to clarify so everyone is aware...

I do not take exogenous T, as a matter of fact, I don't take anything except the following; which I believe are causing my elevated levels...

I've always tested within the 400-600 range in T until I started taking 7.5mg of Remeron at night (started on 10.8.14) and taking approx. 25mg Trazodone at night (started around the same time).

I'm currently at 15.25mg Valium... doing a micro taper of .25mg every 14 days (I came across some study that Valium increases T levels by 20 or 30% but can't seem to find it now).

Hope this helps with clarification.

The main reason is; benzo withdrawal is pure hell... Don't think anyone on here knows about it but, it makes coming off heroin a walk in the park...

and I suffer from insomnia, possibly due to tolerance withdrawal from the benzo since I've been on them for approx 6 yrs.

Don't mean to overwhelm ppl, but just want to paint a better picture.

My main reason for seeking treatment was for growth hormone treatment initially. I was truly hoping to be prescribed anti-aging hgh to benefits from the smoother skin, better mood, better sleep, etc...I always knew I had sub-clinical hypothyroidism and never treated it due to most endo's not treating with desiccated meds and only prescribing t4's... The adrenal fatigue is a hit or miss, I believe it to be true but most of the medical community laughs at the idea.

Hope this helps....

[OingoBoingo]

Just want to clarify so everyone is aware...

I do not take exogenous T, as a matter of fact, I don't take anything except the following; which I believe are causing my elevated levels...

I've always tested within the 400-600 range in T until I started taking 7.5mg of Remeron at night (started on 10.8.14) and taking approx. 25mg Trazodone at night (started around the same time).

I'm currently at 15.25mg Valium... doing a micro taper of .25mg every 14 days (I came across some study that Valium increases T levels by 20 or 30% but can't seem to find it now).

Hope this helps with clarification.

The main reason is; benzo withdrawal is pure hell... Don't think anyone on here knows about it but, it makes coming off heroin a walk in the park...

and I suffer from insomnia, possibly due to tolerance withdrawal from the benzo since I've been on them for approx 6 yrs.

Don't mean to overwhelm ppl, but just want to paint a better picture.

My main reason for seeking treatment was for growth hormone treatment initially. I was truly hoping to be prescribed anti-aging hgh to benefits from the smoother skin, better mood, better sleep, etc...I always knew I had sub-clinical hypothyroidism and never treated it due to most endo's not treating with desiccated meds and only prescribing t4's... The adrenal fatigue is a hit or miss, I believe it to be true but most of the medical community laughs at the idea.

Hope this helps....

Sorry, my bad. I assumed you were on TRT.

If it were me, I'd want to find out why my E2 was so high. You don't want to live with high E2.

[Keep_It_Moving]

Sorry, my bad. I assumed you were on TRT.

If it were me, I'd want to find out why my E2 was so high. You don't want to live with high E2.

The problem is, it wasn't the e2 ultra sensitive, it was just adult estradiol... regular...

I called the lab (which is a hospital that has a laboratory and they said they send it out to ARU Labs) and didn't have the ranges...

bunch of idiots... oh well...

[Keep_It_Moving]

Sorry, my bad. I assumed you were on TRT.

If it were me, I'd want to find out why my E2 was so high. You don't want to live with high E2.

What are some of the consequences of living with high e2? or slightly high... I do have relatively high natty t levels... but i presume these are due to my other meds..
vaium, remeron and traz...

if looking at ratio 52 e with t at 823 and 79 e with 708 t

[OingoBoingo]

What are some of the consequences of living with high e2? or slightly high... I do have relatively high natty t levels... but i presume these are due to my other meds..
vaium, remeron and traz...

if looking at ratio 52 e with t at 823 and 79 e with 708 t

According to LEF:

... excess estrogen contributes to the development of atherosclerosis.

Men with even slightly elevated estrogen levels doubled their risk of stroke and had far higher incidences of coronary artery disease.

Our early observations also revealed that men presenting with benign prostate enlargement or prostate cancer had higher blood estrogen levels (and often low free testosterone blood levels).

Also from LEF:

A study published in the Journal of the American Medical Association (JAMA) measured blood estradiol (a dominant estrogen) in 501 men with chronic heart failure. Compared to men in the balanced estrogen quintile,... men in the highest estradiol quintile were 133% more likely to die.

The men in the balanced quintile—with the fewest deaths—had serum estradiol levels between 21.80 and 30.11 pg/mL. This is virtually the ideal range that Life Extension® has long recommended male members strive for.

The men in the highest quintile who suffered 133% increased death rates had serum estradiol levels of 37.40 pg/mL or above.

The dramatic increase in mortality in men with unbalanced estrogen (i.e., estradiol levels either too high or too low) is nothing short of astounding.

[2Sox]

Deleted post.

Irrelevance

[OingoBoingo]

If you're not using exogenous testosterone and your LH is still in the game, Adex actually might not crash the E2. Correct me if I'm wrong, but all the studies I'm able to find of Anastrozole in males, are done on a normal males with elevated E2. Doses have been 0,5mg or 1mg daily. In those studies it seem to decrease E2 around 50% regardless of the dose. So it significantly lowered their E2, but didn't crash. Unlike it does when on gear. I'm not sure if I'm able to post any links, but the studies are quite easy to find. Anyway, just something to think of.

There's a lot we don't understand yet, but we are learning more every year.

I read something last night about a large dose of Anastrozole causing a double spike of Testosterone in normal men; one upon taking, and another four days later. One doctor opined that this is a common response when we over-regulate our system.

In my case, I didn't take Anastrozole before TRT, but on TRT I know that taking Anastrozole more often than I have symptoms will crush E2.

There is a lot of bro-science around from reading package inserts that were written perhaps 60 years ago, that 100mg of Testosterone is the proper starting dose for TRT. Yet 2014 saw Dr. Crisler lowering his starting dose to 70mg per week, and Dr. Gordon lowering his starting dose to 60mg per week. There's gotta be a reason for that!