I def dropped the ball using lstane a few years back when the school of thought was eod dosing was ok. I developed gyno late in my cycle and it just so happens Jimmyinkedups thread came out so I was at least able to learn the cause. I use adex now only because I stockpiled some pharmgrade and finances. I feel they are both effective when dialed in properly which I feel can be probably the trickiest aspect of cycling especially if you are somewhat e2 sensitive.