i dont think guys are using 250mg per week for TRT, thats more of a cruise when blasting steroids, and if it was for TRT , sooner or later they will end up feeling rubbish like i did, for over 3 years i cruised on 250mgPW and all of a sudden i felt rubbish, lab after lab and no idea what was wrong, dropped dose to 125mg/pw and long story short i felt heaps better.