10X10 training is exactly what I do.... It's been working great for me. I started in sept last year and with diet it's been working to my personal satisfaction.
Im not using it for strength training, it's more for caloric burn and overall conditioning. Your mileage may vary. I also do cardio on my off days.
Sunday legs (10 sets of 10) squats, extensions, leg curls and calf raises. (Legs are smoked for 3 days.
Monday is rows, lat pulls and rotator cuff
Tuesday is usually abs and biceps, again these are 10X10 using any isolating exercise variations.
Wednesday cardio, elliptical or stationary bike. 40 min
Thurs is back day with dead lifts, sumo's and back extensions
Friday rest of do a little 20 minute statinary bike at home
Saturday is chest and triceps....10X10 again and weekday mixing flys, dumb bells and barbells.
Again your mileage may vary....
Eat right.... Lose weight in the kitchen and get fit in the gym