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Thread: Why do i feel like crap? Recently started TRT

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  1. #1
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    Quote Originally Posted by bizzarro View Post
    AI is probably overdosed indeed. TU won't aromatize a lot like test C/E due to slower ester cleavage. Anyway t/2 is about five weeks, three months is the average interval between injections.
    Nebido Functions & Traits:

    Nebido is a pure testosterone hormone attached to the very large Undecanoate ester (Testosterone Undecanoate). The ester is attached to the hormone in order to regulate its release pattern, but it does not affect the testosterone hormones mode of action in anyway. The functions and traits of Nebido on a hormonal basis will be the same as all testosterone compounds.

    Nebido, as a testosterone hormone, like all testosterone hormones carries an anabolic rating of 100 as well as an androgenic rating of 100. This is an estrogenic anabolic steroid in that it does aromatize at a fairly significant rate. As a testosterone compound, Nebido will also carry one of the longest half-lives of any testosterone or anabolic steroid available. Nebido carries an active half-life of approximately three months. Compare this to the more popular Testosterone Cypionate and Testosterone Enanthate, which both carry half-lives a little greater than a week and you can begin to understand how slowly acting Nebido will be.

  2. #2
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    Quote Originally Posted by Silabolin View Post
    Nebido Functions & Traits:

    Nebido is a pure testosterone hormone attached to the very large Undecanoate ester (Testosterone Undecanoate). The ester is attached to the hormone in order to regulate its release pattern, but it does not affect the testosterone hormones mode of action in anyway. The functions and traits of Nebido on a hormonal basis will be the same as all testosterone compounds.

    Nebido, as a testosterone hormone, like all testosterone hormones carries an anabolic rating of 100 as well as an androgenic rating of 100. This is an estrogenic anabolic steroid in that it does aromatize at a fairly significant rate. As a testosterone compound, Nebido will also carry one of the longest half-lives of any testosterone or anabolic steroid available. Nebido carries an active half-life of approximately three months. Compare this to the more popular Testosterone Cypionate and Testosterone Enanthate, which both carry half-lives a little greater than a week and you can begin to understand how slowly acting Nebido will be.
    Perhaps. Half life just seems to vary a lot between studies.

  3. #3
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    Quote Originally Posted by bizzarro View Post
    Perhaps. Half life just seems to vary a lot between studies.
    If I'm not mistaken, and I may be, some sources list the half life (time it takes for the plasma concentration to be reduced by 50%), and some studies state the terminal half life (time it takes for slowest decrease in the plasma concentration of a drug down to 50%). I'm considering going on Aveed in the future and ran across what seemed to be contrary data.
    Also, to second what BiB said, an AI is rarely needed with this ester of testosterone. There is supposedly much less conversion to E2, little need for dose titration, and it also seems to less prone to causing polycythemia, particularly in older males like myself that tend towards polycythemia.
    At least those were some of the aspects my Dr. was interested in, particularly in my case.
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  4. #4
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    Quote Originally Posted by almostgone View Post
    If I'm not mistaken, and I may be, some sources list the half life (time it takes for the plasma concentration to be reduced by 50%), and some studies state the terminal half life (time it takes for slowest decrease in the plasma concentration of a drug down to 50%). I'm considering going on Aveed in the future and ran across what seemed to be contrary data.
    Also, to second what BiB said, an AI is rarely needed with this ester of testosterone. There is supposedly much less conversion to E2, little need for dose titration, and it also seems to less prone to causing polycythemia, particularly in older males like myself that tend towards polycythemia.
    At least those were some of the aspects my Dr. was interested in, particularly in my case.
    It will definitely work for erythrocytosis. I developed mild anaemia (Hb 12.0) with low t and it did took nebido a whole year to raise it to 13.5 .

    The degree of aromatization obv depends on peak levels, and those seems to vary greatly between individuals. A single shot was enough for me to reach levels above detectable range for immunoassay (my lab reports >13.50 ng/ml).

  5. #5
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    I'm in a similar boat as you. I have primary hypo due to AAS abuse in my early 20's. I think you should try hcg, 250iu 2x/wk. I'm on week 2 of it (been on trt for 5 months now) and I can already feel a huge difference. Other than that, just give it time.

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