The natty truth

[Mr.BB]

What BB said.....

Effects of an oral ghrelin mimetic on body composition and clinical outcomes in healthy older adults: a randomized trial. - PubMed - NCBI

CONCLUSION:

Over 12 months, the ghrelin mimetic MK-677 enhanced pulsatile growth hormone secretion, significantly increased fat-free mass, and was generally well tolerated. Long-term functional and, ultimately, pharmacoeconomic, studies in elderly persons are indicated.

Dont know who wrote that, but its really wrong...

No psychiatric data was gathered in this 2008 trial. By now, MK677 has been ruled out as a commercial drug as there wouldnt be FDA and EU approvals, probably due to the possible psychiatric effects of the chronic state of GH bleed.

If you are going to use it do it for short periods, best would be to switch to Mod GRF 1-29 / GHRP2 combo.

[hammerheart]

Dont know who wrote that, but its really wrong...

No psychiatric data was gathered in this 2008 trial. By now, MK677 has been ruled out as a commercial drug as there wouldnt be FDA and EU approvals, probably due to the possible psychiatric effects of the chronic state of GH bleed.

If you are going to use it do it for short periods, best would be to switch to Mod GRF 1-29 / GHRP2 combo.

I wonder whether a ghrelin agonist would help with my chronic lack of hunger.... how are those even administered? Dosage?

Perhaps it might also help with slow digestion, I known it also works as a GI prokinetic. What are the experiences of the members here?

[Mr.BB]

I wonder whether a ghrelin agonist would help with my chronic lack of hunger.... how are those even administered? Dosage?

Perhaps it might also help with slow digestion, I known it also works as a GI prokinetic. What are the experiences of the members here?

GHRP6 and GHRP2 are ghrelin receptor agonists, and you are right one of the side effects is extreme hunger right after application. Personnaly I had more hunger with GHRP2, ussually ppl report more hunger from GHRP6 tough. Its a real extreme hunger effect minutes after sub-q application, this effect will somewhat fade with time.

Saturation dosage is 100mcg or 1mcg per kg of body weight. Advice you to take GHRP2 coupled with Mod GRF 1-29. If some of your problems are related to low pulsatile GH it will help.