Peptides vs HGh

[Mr.BB]

Pure HGH shuts the pituitary down. End of story. Peptides do not. If you decide to stop HGH, you don't know if - or how -your pituitary will recover and start producing GH on its own. If you're willing to take the chance on HGH, go for it. To me it's a no brainer choice. If you stop peptides, you pituitary carries on its job of GH production.

Sorry Sox, but thats not correct.
Sure, HGH might stop a few pulses, but it has very short life, unless you pin it every 3 hours you are not shutting down the pituitary.
Peptides can increase slightly GH production on pituitary and even locally, but this increase is very poor, totally innefective compared to real exogenous HGH. Peptides also mess with an array of poorly studied hormones, which I would say is a bigger gamble.

[balin]

I have used both over the years. And noticed some side effects with low dose 3 i.u.'s HGH. But haven't seen any real benifits to the peptides except for a better quality of sleep. Mostly interested in the long term an leaning effects it can have as I age.

[Youthful55guy]

Sorry Sox, but thats not correct.
Sure, HGH might stop a few pulses, but it has very short life, unless you pin it every 3 hours you are not shutting down the pituitary.
Peptides can increase slightly GH production on pituitary and even locally, but this increase is very poor, totally innefective compared to real exogenous HGH. Peptides also mess with an array of poorly studied hormones, which I would say is a bigger gamble.

Agree with both. Exogenous HGH does not have a long term affect on the pituitary's ability to secrete HGH. Once the IGF-1 levels come down, you'll revert back to where you were. I have off, on, off, on HGH labs that confirm this.

Also HIGHLY agree with the second part of your post. Peptides are very poorly understood and we don't know what other pituitary hormones they are affecting. I have personal experience that they affect Vasopression (antidiuretic hormone) production. I spent two nights in the hospital and nearly died. Granted, perhaps I'm overly responsive to them, but there's little data.

[kelkel]

Agree with both. Exogenous HGH does not have a long term affect on the pituitary's ability to secrete HGH. Once the IGF-1 levels come down, you'll revert back to where you were. I have off, on, off, on HGH labs that confirm this.

Love to see a data breakdown on this if you don't mind! Or pm me please.

[Youthful55guy]

Love to see a data breakdown on this if you don't mind! Or pm me please.

Sorry to be so late with this. Work has kept me from posting for a while.

"Normal" IGF-1 Range (LabCorp) = 50-194 ng/mL
Off = 146
Off = 121
On = 224 (2 IU per day)
Off = 128
On = 174 (I IU per day)

That's what I have so far. I'm not sure if or how long I'll continue with HGH. The effects of Rx are very subtle and I tend to bloat easily with the stuff, which is why I cut back to 1 IU per day. So far (about 7 months into the on-off-on cycle) about all I've noticed (other than the bloat) is a slight healing of some bothersome tendonitis in the elbows and left shoulder.

[kelkel]

Sorry to be so late with this. Work has kept me from posting for a while.

"Normal" IGF-1 Range (LabCorp) = 50-194 ng/mL
Off = 146
Off = 121
On = 224 (2 IU per day)
Off = 128
On = 174 (I IU per day)

That's what I have so far. I'm not sure if or how long I'll continue with HGH. The effects of Rx are very subtle and I tend to bloat easily with the stuff, which is why I cut back to 1 IU per day. So far (about 7 months into the on-off-on cycle) about all I've noticed (other than the bloat) is a slight healing of some bothersome tendonitis in the elbows and left shoulder.

Really interesting number spread. Thanks Y55G.