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Thread: TRT and Crazy Bulk

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  1. #1
    Quote Originally Posted by kelkel View Post
    Some are more sensitive than others. Remember, elevated test = elevated estrogen, even it it's stimulated via clomid and not exogenous test. T will always turn to E, to what extent depends on many variables. One of the top doc's re clomid recommends low dose adex when taking it.

    Think downstream a bit more. The ER (estrogen receptor) is only blocked in the hypothalamus which is how clomid starts the process of T production. The further turnover of T to E downstream is in no way interrupted.
    So would there be any benefit to continuing the clomephine while doing the TRT? I'm on anastrozole now at 1 mg per week.

  2. #2
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    kelkel is offline HRT Specialist ~ AR-Platinum Elite-Hall of Famer ~ No Source Checks
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    Quote Originally Posted by Obspowerstroke View Post
    Gosh dang brother i dont understand. I want to but if every receptor for estrogen is alredy containing a replacement product... how can it increse. I read your post many times I am not being disrespectful. I just dont understand.
    Keep it simple. Clomid is an estrogen antagonist in the hypothalamus only. Thus your brain thinks there's no estrogen left and ramps up GnRH, thus LH & FSH then testosterone. With T comes more E. Clomid does not prevent a rise in estrogen. No Serm does.

    Quote Originally Posted by Unc15smh View Post
    So would there be any benefit to continuing the clomephine while doing the TRT? I'm on anastrozole now at 1 mg per week.
    Zero benefit. Once on exogenous testosterone clomids effect in the brain is nil. That's a lot of adex for TRT. Make sure you pull BW to make dose titrations properly. Use a Sensitive E2 Assay, not standard estradiol if possible.
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