Does Anyone Regret Going on TRT?

[waylaid69]

Exactly what I was thinking.

We all have to keep in mind that this forum is a mix of guys with different backgrounds and goals. For those of us that do TRT because we have a medical need for it unrelated to AAS abuse, it's no different than taking a blood pressure medication. What choice do you have? Pay the consequences of not doing it?

And while I'm on my soap box, I think guys tend to make it much more complicated than it has to be. Most guys will do just fine on 50 mg injected twice weekly. Assuming you do not have other complications like high or low SHBG), this amount should keep your Total and Free T within physiological ranges at all times. Since there are no huge spikes in T, there are no huge spikes in conversion to E2. Therefore, you probably do not need an E2 inhibitor (or very low doses at the most).

I inject 0.5 mL (40 mg) every 3 days. I use a 28G needle (slightly bigger than a mosquito bite). It takes me about a minute to draw up and about 5 seconds to inject. The entire process takes about 7 minutes out of my week and I've been doing this for well over 5 years. If you can't afford 7 minutes in a week, then no, you should not be on TRT.

Youthful55guy, what length needle do you use and what part of the body do you inject?

[Youthful55guy]

Youthful55guy, what length needle do you use and what part of the body do you inject?

1/2 inch (12.7 mm) into the upper outer quad.

[waylaid69]

1/2 inch (12.7 mm) into the upper outer quad.

Ok. Do you think it would work just as well if you used the same needle but injected into the glute, or would that result in too much aromatization?

[Youthful55guy]

Ok. Do you think it would work just as well if you used the same needle but injected into the glute, or would that result in too much aromatization?

I doubt it would have any effect on aromatization. Aromatization mostly follows first order kinetics; the greater the substrate, the greater the conversion. If you lower the substrate level by lowering the peek T value, you lower the conversion.

I don't understand though, why you would want to continue contorting yourself to inject such a small amount into the glute? Injection into the upper outer thigh is so much easier.

[waylaid69]

I doubt it would have any effect on aromatization. Aromatization mostly follows first order kinetics; the greater the substrate, the greater the conversion. If you lower the substrate level by lowering the peek T value, you lower the conversion.

I don't understand though, why you would want to continue contorting yourself to inject such a small amount into the glute? Injection into the upper outer thigh is so much easier.

It's just that I have hit nerves many times when I've injected into the outer upper quad. How far down from the greater trochanter do you inject?
Regarding the aromatization, my doc once told me that if I use a needle that is too short when injecting into the glutes I will just be injecting into fat, which will cause more conversion to estradiol.

[Youthful55guy]

It's just that I have hit nerves many times when I've injected into the outer upper quad. How far down from the greater trochanter do you inject?
Regarding the aromatization, my doc once told me that if I use a needle that is too short when injecting into the glutes I will just be injecting into fat, which will cause more conversion to estradiol.

The Subcutaneous/fat conversion issue is much debated. Dr. Crisler (a notable expert on the subject) says no. Who knows?

Regarding injection site, below is a diagram of the target area I go for. Got this from a former doc many years ago.