
Originally Posted by
Youthful55guy
Not sure I understand the last question. Male E2 levels are normally between 8-35 pg/mL using the sensitive assay (for men). If your total T is low, then you E2 is probably also low, since E2 is derived downstream from esterification of T. I was just saying that getting E2 labs now, or any labs for that matter, are going to be worthless until that initial 200 mg shot clears your system and your system has had a chance to adjust back to your normal state. This takes anywhere from 4 to 6 weeks.
Your LH and FSH levels that you posted were in the normal range, but your Total T and Free T is very low. Your SHBG is on the low side. I suspect you are a rapid metabolizer of T rather than you being primary gonadotropic. Most guys with low SHBG are rapid metabolizers. There's no way that I know up to amp up your SHBG. My gut reaction is to try TRT with small frequent injections. This seems to work best for guys with low SHBG from what I've read in the forums (I have the opposite problem, so I'm not speaking from experience). I would suggest you start out at 40 mg every 2 days (using an insulin syringe) and then get labs in about 4 to 6 weeks. If you are still low, then bump it up to 50 mg E2D and repeat labs in 4 to 6 weeks.
If you are not primary hypogonadotropic, then HCG should work well to preserve fertility. I know of at least 2 guys in the forums that got their wife pregnant on TRT with just 500 IU per week. I would recommend 1000 IU per week in 3 divided doses (e.g., about 350 IU on M,W, F). There's good published data that that is the optimal dose for guys on TRT to preserve fertility.