This a really cool graphic that explains how chemists modified testosterone to make all the derivatives we see on the market. Many steroids and prohormones start as test, and then are modified by one or more of these ways. For example, 19-nor steroids like Deca and tren, all remove the angular methyl group(carbon 19). All orals add an alpha methyl group on 17 to enhance bioavailability. Both EQ and Dbol add a double bond between carbon 1-2. Stanazolol attaches a pyrazole ring to the A-ring. Halodrol added a chlorine atom to carbon 4 to protect against conversion to DHT. All injectables add an ester on the OH in carbon 17 to change the delivery time. Attaching a 7alpha methyl group has been shown to greatly enhance anabolic ratio. Superdrol and anadrol add a group to carbon 2 to help protect the crucial C=O on carbon 3 needed for binding. Trestolone added the 7a methyl group to prevent DHT and SHBG binding. There are literally 100s of modifications you can make to change the effects by changing the binding affinity to the AR. I just thought this was cool and maybe can give a little insight on why certain anabolics act the way they do in the body.
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