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Thread: 37 y/o contemplating TRT, pls help him

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  1. #1
    Join Date
    Jan 2018
    Posts
    172
    Update:

    6 days after that single dose of 12.5mg clomid I had a BW done. Interesting that total T got higher just from that, but since the half life of clomid is pretty long (5-7 days, right?), it makes sense. LH isn't that higher, so I wonder how that works lol.
    The E2 test can't measure lower values than mine, so it's possible that I have low E2. Maybe that's why I have sides? Unfortunately I don't have access to a better lab but I'll keep looking.

    Took a baby dose of 7mg yesterday, felt like crap again, like i have the flu. The plan is to run it for around 5 days, and hope that the sides get better, and to rule out possible nocebo effects after my first encounter with this poisonous substance.

    TT 16.6 nmol/l (479 ng/dl) 6 - 27
    LH 2.6 IU/l 1.2 - 8.2
    FSH 4.4 IU/l 1.3 - 19.3
    SHBG 47.6 nmol/l 13.3 - 89.5
    Cortisol 314 nmol/l 185 - 624
    E2 73 pmol/l (19.9 pg/ml) 0 - 172

  2. #2
    Join Date
    May 2016
    Posts
    1,218
    Quote Originally Posted by Ephemeral View Post
    Update:

    6 days after that single dose of 12.5mg clomid I had a BW done. Interesting that total T got higher just from that, but since the half life of clomid is pretty long (5-7 days, right?), it makes sense. LH isn't that higher, so I wonder how that works lol.
    The E2 test can't measure lower values than mine, so it's possible that I have low E2. Maybe that's why I have sides? Unfortunately I don't have access to a better lab but I'll keep looking.

    Took a baby dose of 7mg yesterday, felt like crap again, like i have the flu. The plan is to run it for around 5 days, and hope that the sides get better, and to rule out possible nocebo effects after my first encounter with this poisonous substance.

    TT 16.6 nmol/l (479 ng/dl) 6 - 27
    LH 2.6 IU/l 1.2 - 8.2
    FSH 4.4 IU/l 1.3 - 19.3
    SHBG 47.6 nmol/l 13.3 - 89.5
    Cortisol 314 nmol/l 185 - 624
    E2 73 pmol/l (19.9 pg/ml) 0 - 172
    LH and FSH are highly episodic, so it's hit or miss with the blood draw. I would not place much value in the fact they are only small increases.

    Why are the units different in your TT with this test (nmol/l) and your previous test (ng/dL). Makes comparisons difficult. I'll take your word that TT went up, which indicates that the clomid is working despite the marginal difference in gonadotropin labs (again, they are episodic).

    I wouldn't run the E2 test if you can't get the right one. Bad information with the wrong E2 test is worse than no information at all.

    You might want to consider taking the clomid at night. More than half of your daily Gonadotropin secretion is during sleep, so having higher clomid levels at night would probably result in a more pronounced effect for the same dose.

  3. #3
    Join Date
    Jan 2018
    Posts
    172
    Quote Originally Posted by Youthful55guy View Post
    LH and FSH are highly episodic, so it's hit or miss with the blood draw. I would not place much value in the fact they are only small increases.

    Why are the units different in your TT with this test (nmol/l) and your previous test (ng/dL). Makes comparisons difficult. I'll take your word that TT went up, which indicates that the clomid is working despite the marginal difference in gonadotropin labs (again, they are episodic).

    I wouldn't run the E2 test if you can't get the right one. Bad information with the wrong E2 test is worse than no information at all.

    You might want to consider taking the clomid at night. More than half of your daily Gonadotropin secretion is during sleep, so having higher clomid levels at night would probably result in a more pronounced effect for the same dose.
    I used the same lab as before, but in my first post I converted the nmol/l numbers to ng/dl (including ranges) because I thought that u guys were more used to that metric. This time I thought it doesn't matter, sorry for the confusion.

    I agree with u that acting on bad information can cause more harm than good, but I was too curious not to throw in E2 as well. I've found a new lab that uses a similar method (Direct CLIA), but slightly more accurate, measuring range is 11.9 - 3000 pg/ml (with suggested range for males is 0 - 39.8), but I guess that's not good enough either due to the fact that it's inaccurate at the lower part of the range.
    Thanks for taking the time to help me guys!
    Last edited by Ephemeral; 01-26-2018 at 03:59 PM.

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