Attachment 172042
Figure 2 from: Coviello, A.D., Matsumoto, A.M., Bremner, W.J., Herbst, K.L., Amory, J.K., Anawalt, B.D., Sutton, P.R., Wright, W.W., Brown, T.R., Yan, X., et al. (2005). Low-dose human chorionic gonadotropin maintains intratesticular testosterone in normal men with testosterone-induced gonadotropin suppression. J Clin Endocrinol Metab 90, 2595-2602.
Serum T during the treatment phase by group. Values are the mean SEM (bars). The shaded box represents the normal reference range of serum T in healthy men for this assay. Serum T increased from baseline in all four groups in response to TE (200 mg, im, weekly; P0.05) and remained elevated during the treatment phase. The two higher hCG dose groups (250 and 500 IU, sc, every other day) had serum T levels above the normal range during the treatment phase.
The above graph shows that 125 IU HCG E2D (438 IU/wk) did not significantly affect T production in 6 healthy young male volunteers receiving 200 mg T-Eth per week. However both 250 IU E2D (875 IU/wk) and 500 IU E2D (1,750 IU/wk) were effective in increasing serum T levels. In both groups, there was an equivalent boost of about 10 nmol/L (~290 ng/dL).