concerned about Bloodwork... help needed

[Youthful55guy]

Hello All,

Just had new Bloods done, Doctor ordered all but SHBG and Estrodial, (not a sensitive assay but all they will do in Canada) I privately paid for the shbg and estro as they can be denied because critia not being met,not a complete requisition on his part as he left out Thyroid knowing I am on synthroid, will discuss this with him on follow up.

I am quite concerned with my lipids, although I was taking winstrol low dosage 10mgs a day to lower my SHBG as my libido was very poor, I have been feeling great, just no Libido, not sure if it was from taking 10 weeks of deca (low dosage as well 100mgs a week) for a cramp I had in my butt in December which made me completely out of commission, I am still recovering, but it is about 90%, it is a long boring story, so I will spare you all. although the day after my first dose, it was tolerable, and improved immensley over the term of use, at least I could go to the gym.

Because of the deca I was concerned about Prolactin, or Shbg, I chose the winstrol over Caber, as I thought maybe it was the least hazardous of the 2. Its hard to get tests you want here.

also my PSA is elevated, was this because of winny or deca? what to do to lower it?

I am on TRT, 40 mgs every 3.5 days,,, I am 60 years old
thank you for your time

In my experience, 10 mg Winstrol to control high SHBG is about double what you need. This is evident in your labs, which shows you are at the bottom of your range. What were you levels before treatment? Also consider that exogenous thyroid hormone (Synthroid in your case) will drive up SHBG. If you need the Synthroid, and you have labs to justify it, then go ahead and take it. However, understand that there is good data to show that it drives up SHBG. Perhaps that's the root of your problem and you are treating side-effects rather than a core problem.

Your total T is not all the great, but your free T is good. The reason for total T being on the low side is that SHBG is low. SHBG protects T from liver metabolism. On the other hand, SHBG also binds T and prevents it from crossing the blood brain barrier, so free T is the more important of the two labs. Personally, I'd lower the Winstrol dose to 5 mg/day to get SHBG up slightly. That will bring your Total T down up and your free T down slightly. Then I'd consider a very slight T adjustment upward (perhaps to 50 mg) to bring the free T back to mid-range.


Your PSA is high. There is nothing that can treat this that I know of. PSA can (not always) is a sign of prostate cancer, but sometimes it's just high without cancer (false positive). I'd HIGHLY consider a digital prostate exam. Also, be careful about biopsies, they can cause more damage and send up PSA even higher. I'm not an expert on this subject, but perhaps others with more experience can comment on the high PSA.

[ryobi1]

In my experience, 10 mg Winstrol to control high SHBG is about double what you need. This is evident in your labs, which shows you are at the bottom of your range. What were you levels before treatment? Also consider that exogenous thyroid hormone (Synthroid in your case) will drive up SHBG. If you need the Synthroid, and you have labs to justify it, then go ahead and take it. However, understand that there is good data to show that it drives up SHBG. Perhaps that's the root of your problem and you are treating side-effects rather than a core problem.

Your total T is not all the great, but your free T is good. The reason for total T being on the low side is that SHBG is low. SHBG protects T from liver metabolism. On the other hand, SHBG also binds T and prevents it from crossing the blood brain barrier, so free T is the more important of the two labs. Personally, I'd lower the Winstrol dose to 5 mg/day to get SHBG up slightly. That will bring your Total T down up and your free T down slightly. Then I'd consider a very slight T adjustment upward (perhaps to 50 mg) to bring the free T back to mid-range.


Your PSA is high. There is nothing that can treat this that I know of. PSA can (not always) is a sign of prostate cancer, but sometimes it's just high without cancer (false positive). I'd HIGHLY consider a digital prostate exam. Also, be careful about biopsies, they can cause more damage and send up PSA even higher. I'm not an expert on this subject, but perhaps others with more experience can comment on the high PSA.

Thanks for the response Youthful,
I didnot check bloods before comencing with the winstrol, I only ran it for 2 weeks, and have been off for about that now, I think the winstrol is what messed up my lipids, so when I seen the results I stopped the Winstrol.
as for the synthroid, I had half my thyroid removed years ago, and was doing fine until about 3 years ago, and my antibodies and tsh were through the roof, so I was put on synthroid, 50 mcg, and since last year upped to 75mcg,s
I know maybe a dumb question, but which T is important for the Brain? total T or free T.

I did go to a different Lab for the PSA than before when I was in range, but I dont get how the ranges can very so much from lab to lab, especially when they are all the same syndicate lab. but that probably because I'm not a scientist

[Youthful55guy]

Thanks for the response Youthful,
I didnot check bloods before comencing with the winstrol, I only ran it for 2 weeks, and have been off for about that now, I think the winstrol is what messed up my lipids, so when I seen the results I stopped the Winstrol.
as for the synthroid, I had half my thyroid removed years ago, and was doing fine until about 3 years ago, and my antibodies and tsh were through the roof, so I was put on synthroid, 50 mcg, and since last year upped to 75mcg,s
I know maybe a dumb question, but which T is important for the Brain? total T or free T.

I did go to a different Lab for the PSA than before when I was in range, but I dont get how the ranges can very so much from lab to lab, especially when they are all the same syndicate lab. but that probably because I'm not a scientist

Unless you are documented as being high on SHBG, I would not mess with Winstrol. yes, it can mess up your lipids and it is also hard on the liver. I don't seem to have a problem with either at 5 mg, but I do monitor them closely. At 10 mg, I noticed an increase in liver enzymes to just slightly above range. At 15 mg, definitely above range.

Now, coming off Winstrol, your SHBG will increase, and with your low Total T, your free T will drop. I looks to me like you are a good candidate for TRT.

Since you have thyroid issues, I would focus on treating that to get those levels in range. I'm not a big fan of T4 only treatment, but that's up to you and your doc. I prefer to use Armour Thyroid, wich has a good balance of all 4 thyroid hormones.

[ryobi1]

Unless you are documented as being high on SHBG, I would not mess with Winstrol. yes, it can mess up your lipids and it is also hard on the liver. I don't seem to have a problem with either at 5 mg, but I do monitor them closely. At 10 mg, I noticed an increase in liver enzymes to just slightly above range. At 15 mg, definitely above range.

Now, coming off Winstrol, your SHBG will increase, and with your low Total T, your free T will drop. I looks to me like you are a good candidate for TRT.

Since you have thyroid issues, I would focus on treating that to get those levels in range. I'm not a big fan of T4 only treatment, but that's up to you and your doc. I prefer to use Armour Thyroid, wich has a good balance of all 4 thyroid hormones.

Thanks again Youthful...
ya, I was just worried my SHBG might have been the culprit for low libido, I have learned a lesson about the winstrol. but with my lipids going askew, it seems like a fairly harsh compound.

That does sound like a bad thing total T increasing and free T lowering, as most docs look at total T and say, "You're fine", I am on TRT, but the level of compitence of doctors treating people up here is pretty sad, you have to be recommended to a Endo, or Urologist by your doc, so if you dont have a legit reason, you wont get one.
The endo I was sent to was archaic, and not sure if he cared to get enlightened on the protocols by those leading the way, he was in his 70s, so set in his ways i guess.

that was another discussion I meant to have was about the armour thyroid, they seem to only be concerned if your TSH in range. the endo I was seeing did run freet3 freet4 and TSH.. probably why he said I graduated, which I thought was thr strangest thing... these problems as I know, dont go away.

Thyroid Function
TSH 3.56 0.32-5.04 mU/L
T4 Free 13.7 10.6-19.7 pmol/L
T3 Free 3.44 3.00-5.90 pmol/L

Test results from last december.