I will say I really like this cycle, and the dosages are spot on imo. I'm guessing your goal with this cycle is to put on some size.
unless your super estrogen sensitive, the high dose of test and the aromatiziation into estrogen is going to HELP the Tren work better at putting on size . so I wouldn't over do the AI usage (me personally , I wouldn't run an AI at all on this cycle , I'd just run 10mg per day of Nolva).
Also, if you are worried about and sensitive to estrogen. Keep in mind that an AI does NOTHING for the estrogenic effects of Anadrol . Anadrol is very estrogenic, but NOT from being converted by the aromatase enzyme (therefore an AI does nothing). with Anadrol you have to limit estrogen at the receptor site itself, so you have to use a SERM to block its estrogenic activity (not an AI).
having said that , again if growth is the goal, then I'd not restrict estrogen too much as Tren works much better as a mass builder when estrogen levels are high , and much better as a cutting agent when estrogen is low.
As for Letro. its great to have on hand for sure. I use letro, but only for short 2 week runs just in case my Estrogen gets WAY too high and out of control. letro is fast and effective. but like octane said, its a little harder to manage for the long term on cycle then Adex is.
but like I said. you don' need an AI at all for this cycle .. just a SERM imo.
to answer you're question though, no there are no issues going from adex to letro