Real IGF (Increlex) vs Peptide IGF LR3 - Cost

[GearHeaded]

A bitt off but u sound like an indepth guy.
Whats your take on mk677...honestly?

I've ran MK-677 off and on for a few years . I have clients running it as well. generally 25mg at night along with 5mg of Melatonin (which helps produce an even stronger pulse)... for people that are wanting to benefit from the increase in appetite , I'd have them do 12.5mg at night and another 12.5mg the next day.
for some people this can be equivalent to running a couple IU of HGH per day.

the only problem I have with MK-677 personally (not everyone) is that it really ramps up my fasted blood sugar big time .. from 80 to over 100. so when I'm running MK I'm usually running insulin in the AM as well (and not just insulin pre and post workout).

I also have no problem stacking MK with exogenous GH, to 'amplify' growth hormone levels. LOTS of benefits to MK imo, and very few side effects

[AR's King Silabolin]

I've ran MK-677 off and on for a few years . I have clients running it as well. generally 25mg at night along with 5mg of Melatonin (which helps produce an even stronger pulse)... for people that are wanting to benefit from the increase in appetite , I'd have them do 12.5mg at night and another 12.5mg the next day.
for some people this can be equivalent to running a couple IU of HGH per day.

the only problem I have with MK-677 personally (not everyone) is that it really ramps up my fasted blood sugar big time .. from 80 to over 100. so when I'm running MK I'm usually running insulin in the AM as well (and not just insulin pre and post workout).

I also have no problem stacking MK with exogenous GH, to 'amplify' growth hormone levels. LOTS of benefits to MK imo, and very few side effects

Looks familiar. Sometimes when i hit the gym and i get too exicted talking to another juichead during a hard warmup, whom i find very interessting, i sometimes feel bad an my hunger explodes. Need to buy 2 proteinbars etc and i wanna eat anyting.

Palumbo says mk677 should be run at 25 mg every morning, not evenings.
I think he said because during sleep its naturally high and u need it more when the day comes.

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[GearHeaded]

Palumbo says mk677 should be run at 25 mg every morning, not evenings.
I think he said because during sleep its naturally high and u need it more when the day comes.

well I'll have to look into that some more .. but my reasoning for taking MK at night along with a Somatostatin inhibitor, is because MK as a GH secretagouge is going to 'amplify' our natural growth hormone pulses making them produce more GH. being we have the most pulses at night, in seems reasonable to increase the strength of these pulses during this time with the MK.
Also, MK's effect on the pituitary is limited by the bodies glucose metabolism . so if you have too many carbs from eating flowing in your blood, then MK's effect of releasing natural growth hormone is going to be limited .. at night/sleep we are not eating and so MK won't be effected by this.

I will say . this is just the OPPOSITE with exogenous HGH administration . We do NOT want to inject HGH at night before bed, because we will turn off our own production of GH from the pituitary . but MK-677 is not like this, it works to help the pituitary produce MORE GH release at night.

IF I do take MK-677 at night as well as the next day, I make sure the next day its taken in fasted condition and not eat for at least an hour afterwards.
with exogenous HGH itself, it doesn't matter though as thats going right into the blood stream completely independent of the pituitary or glucose metabolism . so you can take HGH anytime . MK works better fasted.
BUT , I'm open to learning more. maybe I'm off in my thinking here.

[AR's King Silabolin]

well I'll have to look into that some more .. but my reasoning for taking MK at night along with a Somatostatin inhibitor, is because MK as a GH secretagouge is going to 'amplify' our natural growth hormone pulses making them produce more GH. being we have the most pulses at night, in seems reasonable to increase the strength of these pulses during this time with the MK.
Also, MK's effect on the pituitary is limited by the bodies glucose metabolism . so if you have too many carbs from eating flowing in your blood, then MK's effect of releasing natural growth hormone is going to be limited .. at night/sleep we are not eating and so MK won't be effected by this.

I will say . this is just the OPPOSITE with exogenous HGH administration . We do NOT want to inject HGH at night before bed, because we will turn off our own production of GH from the pituitary . but MK-677 is not like this, it works to help the pituitary produce MORE GH release at night.

IF I do take MK-677 at night as well as the next day, I make sure the next day its taken in fasted condition and not eat for at least an hour afterwards.
with exogenous HGH itself, it doesn't matter though as thats going right into the blood stream completely independent of the pituitary or glucose metabolism . so you can take HGH anytime . MK works better fasted.
BUT , I'm open to learning more. maybe I'm off in my thinking here.

Ur actually knowledeable. 50% says moning. 50% says evening. I used to do 12.5 mg evening and 12.5 mg morning. With better results than once a day.
But when Dave said this, i do every thing in the morning. It works. But its impossible to say which is better.

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[Ashop]

I've ran MK-677 off and on for a few years . I have clients running it as well. generally 25mg at night along with 5mg of Melatonin (which helps produce an even stronger pulse)... for people that are wanting to benefit from the increase in appetite , I'd have them do 12.5mg at night and another 12.5mg the next day.
for some people this can be equivalent to running a couple IU of HGH per day.

the only problem I have with MK-677 personally (not everyone) is that it really ramps up my fasted blood sugar big time .. from 80 to over 100. so when I'm running MK I'm usually running insulin in the AM as well (and not just insulin pre and post workout).

I also have no problem stacking MK with exogenous GH, to 'amplify' growth hormone levels. LOTS of benefits to MK imo, and very few side effects

I like MK677 really well but dosages over 12.5mg make me REALLY tired! I use my HGH in the morning and my MK677 right before bed.