Test c and Ostarine cycle

[AR's King Silabolin]

yeah think so .. probably would be pointless to run Osta and LGD together. just run a higher dose of LGD cause I don't think the Osta is going to provide the receptor any additional information then what the LGD does .

which is different then actual AAS.. running 5 different steroids can provide 5 unique sets of information to the cell (eg, test + tren + mast + winstrol + primo, will all bind to receptors individually, transduce coding to the cell, and then move on to another receptor, all providing DNA its own unique muscle building code).

I'm not sure that SARMS work quite the same way though. as they are more 'selective' in how they bind and relay information, and AAS are not so much.
to the cell both Osta and LGD may be the same thing essentially.. idk , or they may relay the same "Selective" information to the cell (again as a SARM , ie, Selective Androgen Receptor Modulator) . AAS are all unique and not selective and relay all sorts of different information to cells

Agree. The steroid synergic effect is wellknown for many years.
But, personall experiences tell me it do not relate to sarms.
I dont see much difference from 25 mg LGD and 25 mg LGD and 25 mg S23 even. Maybe little more dry look with the lgd/s23 combi but thats the only thing.
Guess the synergy would be even less with ost n lgd.
But adding mk677 and cardarine to the equation, well that is a complete other story. The effects then just add up if u ask me.

But the most interessting part is studying the synergy beetween sarms and steroids. As we speak my take these days is that that combi dont work as good as expected. I think there will be some competition on the ARs. And the weaker SARMs are not an easy win for the more effective steroids im afraid.
Meaning. Running 500 test 500 deca 25 LGD migth give the same results as 500 test and 500 deca. Or maybe less. As test and deca are ofcourse more effective than lgd but looses space at the receptors for the tripplecombi.
Sent fra min SM-N9005 via Tapatalk

[GearHeaded]

Agree. The steroid synergic effect is wellknown for many years.
But, personall experiences tell me it do not relate to sarms.
I dont see much difference from 25 mg LGD and 25 mg LGD and 25 mg S23 even. Maybe little more dry look with the lgd/s23 combi but thats the only thing.
Guess the synergy would be even less with ost n lgd.
But adding mk677 and cardarine to the equation, well that is a complete other story. The effects then just add up if u ask me.

But the most interessting part is studying the synergy beetween sarms and steroids. As we speak my take these days is that that combi dont work as good as expected. I think there will be some competition on the ARs. And the weaker SARMs are not an easy win for the more effective steroids im afraid.
Meaning. Running 500 test 500 deca 25 LGD migth give the same results as 500 test and 500 deca. Or maybe less. As test and deca are ofcourse more effective than lgd but looses space at the receptors for the tripplecombi.
Sent fra min SM-N9005 via Tapatalk

we are in agreement here with most of what is said , especially about Steroids being more synergetic together then SARMs more then likely..

I'll only point out that we have a different take on how Anaboics work on the androgen receptors themselves.

I don't believe there is any such thing as "receptor competition" between drugs. one drug does not beat out another drug for binding to the androgen receptors (if such competition existed, the body can simply produce a million more androgen receptors in a few days). a steroid does NOT bind to an androgen receptor and stay stuck there indefinitely. it binds to an androgen receptor, relays information to the cell, and then it moves on to the next androgen receptor to do the same thing. and so on and so on. a drug does not bind to the receptors and say "ha, these are my receptors and my receptors only" , no it binds and relays information and moves on, and other drugs can also bind to those same receptors and relay the information that they have to relay.

if you took 20 different steroids at high dosages.. over time all 20 of those drugs would eventually bind to receptors and relay information. there would not be competition where some drugs binds and other drugs get wasted. no they would all eventually bind , and not only that but some receptors would have had all 20 different drugs bound to it at some point (as again, drugs bind to receptors and the detach and move on to others). if one drug has a stronger affinity for AR binding then another drug, it may bind to said receptor first , but again its eventually going to detach and another drug can bind to that same receptor (its not going to hog it long term).

also, keep in mind that there are
class 1 steroids and class 2 steroids.. class 1 steroids are dependent on androgen receptor binding to illicit their magic. class 2 steroids on the other hand are not dependent on androgen receptor binding at all in order to work, as they work through other mechanisms . so of course there can be no competition between these 2 steroids really
example, tren is not going to compete with Anadrol for AR binding, being Anadrol is not dependent on AR binding to work being its a class 2 steroid