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Thread: Need advice on cycle

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  1. #1
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    Quote Originally Posted by i_SLAM_cougars View Post
    How are the Sarms making the AAS less effective?
    If some of the limited amount of androgen receptors are being used by a sarm then the more potent AAS can't use it
    That's my understanding

  2. #2
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    Quote Originally Posted by HoldMyBeer View Post
    If some of the limited amount of androgen receptors are being used by a sarm then the more potent AAS can't use it
    That's my understanding
    see my previous post.. there are more androgen receptors in our bodies then we could ever take gear to fully accommodate. if you took 20 grams of gear per week you still probably wouldn't be able to fully saturate all your androgen receptors. Plus, when you take higher and higher doses your body super compensates and produces more and more androgen receptors . a high dose AAS user is going to have a lot more androgen receptors then someone on TRT for example.. In fact I will purposely blast for a few weeks only super high dosages in an attempt to increase my androgen receptor density (this protocol comes from a guy that was the head chemist at a big pharma company for 25 years and he spent his whole life studying AAS and the androgen receptor).
    but even so, again you still have more androgen receptors then what a little bit of AAS and Sarm's could ever compete over.

    also, keep in mind that class 2 anabolics (like Winstrol and anadrol) work their magic outside of androgen receptor binding. so if they are not dependent on AR binding, then surely the SARM is not going to compete with them


    Also, steroids do not bind to androgen receptors and stay bound their indefinitely.. they bind to a receptor , transcribe information to the cell, and then move on to another receptors.. so there really can be no "competing" for receptors. the AAS and SARMS are binding and then moving on , so everyone gets their turn sort of speak . kinda like a gang bang on a hot chick.
    if a SARM binds to an AR , its not competing with the AAS cause the SARM is just going to bind for a temporary time and then move on to another receptor
    Last edited by GearHeaded; 08-08-2019 at 05:42 AM.

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