Esters do Have an Effect!!!

[Family_guy]

So upon some further research the main difference between “pharmaceutical salts” (sulfate, hydrochloride, etc) and esters is that salts are bonded ionically while esters are bonded covalently. Which means that esters are bonded much “stronger” and they become technically a prodrug to the parent compound since it’s not active biologically until the Ester is cleaved. Where as salts are not prodrugs usually. At least that’s what I was just reading. So anyways maybe my first point isn’t correct scientifically but I know there’s still a ton of anecdotal evidence saying there is a different between esters.

Note-there is a significant difference between effects of morphine sulfate and morphine hydrochloride but maybe it’s not the same as comparing Test Prop vs Cyp for example. Maybe someone with more chemistry knowledge than I could explain the difference better

[Obs]

So upon some further research the main difference between “pharmaceutical salts” (sulfate, hydrochloride, etc) and esters is that salts are bonded ionically while esters are bonded covalently. Which means that esters are bonded much “stronger” and they become technically a prodrug to the parent compound since it’s not active biologically until the Ester is cleaved. Where as salts are not prodrugs usually. At least that’s what I was just reading. So anyways maybe my first point isn’t correct scientifically but I know there’s still a ton of anecdotal evidence saying there is a different between esters.

I just said all tgat ya cunt

[Family_guy]

I just said all tgat ya cunt

Shut up! Lmao

[Family_guy]

I just said all tgat ya cunt

That doesn’t change the fact that different esters do have different effects. I should have put a poll on this thread

[Obs]

That doesn’t change the fact that different esters do have different effects. I should have put a poll on this thread

Mmmmm possibly because people dont know how to dose them according to their half life so that longer esters begin to build up?

They all taste the same to me.

[Family_guy]

Mmmmm possibly because people dont know how to dose them according to their half life so that longer esters begin to build up?

They all taste the same to me.

Vote then mother fugger!

[charger69]

That doesn’t change the fact that different esters do have different effects. I should have put a poll on this thread

Who told you they do t have any effect? Your dog? Obviously not someone who takes AAS. LOL


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[The God Himself]

So upon some further research the main difference between “pharmaceutical salts” (sulfate, hydrochloride, etc) and esters is that salts are bonded ionically while esters are bonded covalently. Which means that esters are bonded much “stronger” and they become technically a prodrug to the parent compound since it’s not active biologically until the Ester is cleaved. Where as salts are not prodrugs usually. At least that’s what I was just reading. So anyways maybe my first point isn’t correct scientifically but I know there’s still a ton of anecdotal evidence saying there is a different between esters.

Note-there is a significant difference between effects of morphine sulfate and morphine hydrochloride but maybe it’s not the same as comparing Test Prop vs Cyp for example. Maybe someone with more chemistry knowledge than I could explain the difference better

Ionic bonds are much stronger than covalent bonds. But the ionic bond here is between the atoms that make the salt, not between salt and drug. When you connect an alcohol with an acid you get esters.
Back to the topic, I think its all about injection frequency. A long ester pinned ED has much stabler blood levels compared to short ester pinned ED. I think SHBG levels play a role here.

[charger69]

Ionic bonds are much stronger than covalent bonds. But the ionic bond here is between the atoms that make the salt, not between salt and drug. When you connect an alcohol with an acid you get esters.
Back to the topic, I think its all about injection frequency. A long ester pinned ED has much stabler blood levels compared to short ester pinned ED. I think SHBG levels play a role here.

Thank you! I think FG had a brain fart. I have mentioned on numerous occasions that I inject long esthers daily for that reason.


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[GearHeaded]

when I decided to run 2000mg of test per week (a big chunk of that being test prop) . I seemed to get drier and harder running that then when running 500mg of test e on a cruise .. now granite, I was on tren and mast , but shit I'm always on tren and mast

[Family_guy]

Hey Redz you voted that it’s a major difference. I’d love to hear your thoughts on this and why you feel that way

[HoldMyBeer]

So upon some further research the main difference between “pharmaceutical salts” (sulfate, hydrochloride, etc) and esters is that salts are bonded ionically while esters are bonded covalently. Which means that esters are bonded much “stronger” and they become technically a prodrug to the parent compound since it’s not active biologically until the Ester is cleaved. Where as salts are not prodrugs usually. At least that’s what I was just reading. So anyways maybe my first point isn’t correct scientifically but I know there’s still a ton of anecdotal evidence saying there is a different between esters.

Note-there is a significant difference between effects of morphine sulfate and morphine hydrochloride but maybe it’s not the same as comparing Test Prop vs Cyp for example. Maybe someone with more chemistry knowledge than I could explain the difference better

NVM, TGH already said it. That's what I get for not reading all the replies first