just to clarify . T3 in and of itself is not 'catabolic' . there is nothing in T3 that is going to raise cortisol levels, and cortisol is the hormone that promotes gluconeogenisis and the break down of muscle tissue for proteins. but yes T3 can easily boost up your metabolic rate and put you in a calorie deficit , which can have secondary side effects of catabolism (obviously being in a deficit can be catabolic).
thats why T3 should be saved for cutting only.
now the combination of T3 and AI's together , this creates a much more catabolic environment.
you ever wonder why women can take massive dosages of T3 for months on end and not seem to lose a single ounce of muscle. yet a guy in contest prep takes half the dosage and he goes flat and seems to lose muscle..
its because the female has way higher estrogen levels, and estrogen is an anti catabolic hormone. the man on the other hand is likely running AI's and keeping his E levels super low, so when he takes T3 with those AI's , he loses muscle much quicker.
drop the AI and keep your E levels higher and you'll be way less prone to losing muscle with T3 or when dieting.
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