Author: Muscle-Research


Stability of IGF... the Truth

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**New Studies showing increased Stability of IGF-I

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Stability Data for LongTMR3IGF-I (Liquid Formulations)

The stability of a liquid solution of LongTMR3IGF-I was monitored for a period of two years at storage conditions of -20 C, +4 C, +22 C, and +37 C. The final concentration of LongTMR3IGF-I was in acetic acid. At various time points, samples were taken and compared to a lyophilized control (stored at 4 C). Listed below are the stability results for each respective storage condition.


 Storage Condition: -20 C


Biological Potency No Change up to 2 years
Immunological Activity No Change up to 2 years
Mobility of Protein No Change up to 2 years
Elution Profile by reversed phased HPLC No Change up to 2 years


 Storage Condition: +4 C


Biological Potency No Change up to 2 years
Immunological Activity No Change up to 2 years
Mobility of Protein No Change up to 2 years
Elution Profile by reversed phased HPLC No Change up to 2 years


 Storage Condition: +22 C


Biological Potency No Change up to 2 years
Immunological Activity No Change up to 2 years
Mobility of Protein No Change up to 2 years
Elution Profile by reversed phased HPLC No Change up to 2 years


 Storage Condition: +37 C


Biological Potency No Change up to 1 year
Immunological Activity No Change up to 1 year
Mobility of Protein No Change up to 1 year
Elution Profile by reversed phased HPLC No Change up to 1 year


 Conclusions

o There is no significant difference in the potency of LongTMR3IGF-I associated with the storage of the liquid formulation when stored at this range of temperatures.
o There is no evidence for loss of biological activity at any of the tested temperatures when stored as a liquid product.



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I dug up this data to help educate people on LR3 IGF-I. The above information was gathered by gropep during experiments which stretched several years.

As you can see IGF can be quite stable for even a year at room temp

-MR
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