Steroids causing Uticeria?

[psmith]

Hi I just wanted to make this post to see if anyone else has had the unfortunate problem of developing chronic Uticeria from steroid use. I have used steroids for a couple of years now and during the time I spent in London I developed this chronic Uticeria. It is the most painful experience you can imagine, where you whole body starts to burn like on fire and you get these wheels all over your body, mine luckily goes away after 15 minutes or so, but I have to get to cool air before it becomes unbearable.

Anyway, that’s a brief description about the pain, and I was told that I have an allergic reaction to testosterone, rather cortisone that is based in Deca-Durabolin what is actually used to treat chronic Uticeria had caused this problem to get worse as now due to the length I have used this drug my body has become dependant on cortisone to help relieve the pain of the Uticeria, as I feel much better when I’m on a cycle, but as soon as I come off I have the most severe outbreaks everyday, most of the day, it has totally wrecked my life as I can’t do anything, (meetings, etc) without worrying about myself breaking out.

Maybe somebody could share some light on this and help with some solutions to cure this problem I have as I can’t even gym anymore and I’m starting to get such depression as I can’t use gear again or train, when I do I suffer and I just can’t go through it anymore, SOMEBODY PLEASE HELP, I’ve tried every type of antihistamine, camomile teas, nettle teas, and nothing has removed this completely now I’m using the a very expensive antihistamine everyday during the day called Cestine, and at night Finnegan, but I’m draining during the day because of the sedative properties of the Finnegan and I would really like to stop having to take something to try eliminate it from breaking out?

[cj1capp]

Urticaria (Hives or "Nettle" Rashes)
by Dr Adrian Morris
Urticaria is a raised itchy and painful skin rash sometimes called a “nettle rash” or hives. There are two distinct types of urticaria:
· Acute urticaria is often caused by an allergy to food or medication and can last between several hours and six weeks.
· Chronic urticaria is diagnosed if the rash persists for six weeks or longer, the underlying cause is then usually not due to food allergies.
What are the causes?

Acute Urticaria

The most likely cause of Acute Urticaria is an allergy due to exposure to pets, horses, latex rubber, food such as shellfish, nuts, egg and dairy products or bee and wasp stings. Allergies to medication such as antibiotics (penicillin, tetracycline, sulphonamides and cephalosporins), blood pressure pills (ACE inhibitors and diuretics), codeine and aspirin containing pain killers can cause acute urticaria. Sometimes viral infections such as glandular fever and hepatitis B, or bacteria (helicobacter, streptococci), fungal and parasitic infections can trigger urticaria. Allergic reactions to blood products, transfusions, xray contrast and vaccines have also been implicated. Papular urticaria is the medical term for “itchy bumps” or grouped urticarial lesions seen mainly in children and which follow insect bites from midges, fleas and mosquitoes.

Chronic Urticaria

The cause of Chronic Urticaria is much more difficult to identify. The role of true food allergy is hardly ever a significant trigger but food additives such as salicylate, sodium benzoate, colourings and nitrites may play a role. We often end up diagnosing Chronic Idiopathic Urticaria. This condition (which can persist for many years) is due to the production of “auto-antibodies” which in turn attack specific Mast Cells in our skin and tissues causing an enormous release of histamine. Why we suddenly switch-on production of these aggressive antibodies to our own skin cells is a complete enigma. Our bodies may continue producing these auto-antibodies for a number of years leading to a great deal of distress and discomfort for the urticaria sufferer. Unfortunately over 50% of Chronic Urticaria cases are due to production of these “auto-antibodies” to the IgE and its receptor on Mast Cells found in the skin.

Chronic parasitic infections and ACE inhibitor blood pressure pills may play a role in both acute and chronic urticaria. Stress is known to aggravate urticaria and stress reduction measures are very important in treating chronic urticaria.

Chronic urticaria can also be triggered by physical factors such as exposure to environmental heat (prickly heat), intense cold, sunlight, vibration or pressure on the skin (from tight clothing). Very rarely some people react to bath water, this is called “Aquagenic” Urticaria. Exercising after eating certain foods such as wheat, celery and shellfish might provoke delayed urticaria. Many people have very sensitive skin and any friction or rubbing will cause raised red lines to develop. This is called Dermatographism and indicates just how easily they can release histamine in their own skin. A good test for cold urticaria is to hold a block of ice against the skin for 5 minutes and see if an urticaria weal develops after the ice is removed.

Underlying thyroid diseases and autoimmune diseases such as Systemic Lupus and Rheumatoid Arthritis can provoke Chronic Urticaria or even Urticarial Vasculitis (a variant in which the lesions tend not to fluctuate but lead to skin discolouration). Urticarial Vasculitis may be associated with a fever, bone pains and joint swelling (Schnitzler’s Syndrome).

Occasionally an inherited deficiency of the C1 Esterase Inhibitor Enzyme leads to a non-itchy form of urticaria called Hereditary or Familial Angioedema. This condition affects mainly females in a family, is associated with sudden swelling of the face and neck which is not itchy but tends to be painful. These lesions usually last for 2 to 3 days and do not respond to antihistamine medication. Sufferers characteristically have low levels of the Complement C4 in their bloodstream and respond to medication called Danazol or Tranexamic acid which prevents attacks.

[psmith]

Hey, thank you for that post, but I have read many sources from that, I have not had any first hand knowldge from people that use steroids that have had this happen to them, the main problem is I really want to get back into training ASAP! and know what type of steroids I can use that I won't have an allergic reaction to. I have found some articles about Stanozolol being used to help cause chronic uticeria. Now i'm wondering if that won't cause more problems? I would really like to be able to get back into the game, I was really starting to get some amazing results and I would really like to be able to start competing! Please if anyone is able to give me some first hand knowledge I would be really great full. I am now seeing a Professor at R200 every 10 minutes! As she has worked first hand with Doctor Green the Uticeria specialist in the UK. And she was the one who told me that Deca-Durabolin had causes alot of the problems due to the cortisone. But thing is I even tried a box of Depo test (Test cypionate) at 1 amp a week (200mg) and that triggered it off, but then again, maybe it was the cortisone cause I just finished that might have also warn off? hmm, its really difficult for me to self diagnose. I have many theories! many of them can lead to me believing that steroids isn't the problem ;P but I best lose that train of thought as the last thing I need to do now is trigger it off any worse.

I don't want to believe its a thyroid problem either! I know that when I was on gear my body was alot warmer so ofcourse I would break out easier as I was right at boiling point before the Uticeria breaks out!

Thanks once again.

[spittin' 'n cussin']

Urticaria (Hives or "Nettle" Rashes)
by Dr Adrian Morris
Urticaria is a raised itchy and painful skin rash sometimes called a “nettle rash” or hives. There are two distinct types of urticaria:
· Acute urticaria is often caused by an allergy to food or medication and can last between several hours and six weeks.
· Chronic urticaria is diagnosed if the rash persists for six weeks or longer, the underlying cause is then usually not due to food allergies.
What are the causes?

Acute Urticaria

The most likely cause of Acute Urticaria is an allergy due to exposure to pets, horses, latex rubber, food such as shellfish, nuts, egg and dairy products or bee and wasp stings. Allergies to medication such as antibiotics (penicillin, tetracycline, sulphonamides and cephalosporins), blood pressure pills (ACE inhibitors and diuretics), codeine and aspirin containing pain killers can cause acute urticaria. Sometimes viral infections such as glandular fever and hepatitis B, or bacteria (helicobacter, streptococci), fungal and parasitic infections can trigger urticaria. Allergic reactions to blood products, transfusions, xray contrast and vaccines have also been implicated. Papular urticaria is the medical term for “itchy bumps” or grouped urticarial lesions seen mainly in children and which follow insect bites from midges, fleas and mosquitoes.

Chronic Urticaria

The cause of Chronic Urticaria is much more difficult to identify. The role of true food allergy is hardly ever a significant trigger but food additives such as salicylate, sodium benzoate, colourings and nitrites may play a role. We often end up diagnosing Chronic Idiopathic Urticaria. This condition (which can persist for many years) is due to the production of “auto-antibodies” which in turn attack specific Mast Cells in our skin and tissues causing an enormous release of histamine. Why we suddenly switch-on production of these aggressive antibodies to our own skin cells is a complete enigma. Our bodies may continue producing these auto-antibodies for a number of years leading to a great deal of distress and discomfort for the urticaria sufferer. Unfortunately over 50% of Chronic Urticaria cases are due to production of these “auto-antibodies” to the IgE and its receptor on Mast Cells found in the skin.

Chronic parasitic infections and ACE inhibitor blood pressure pills may play a role in both acute and chronic urticaria. Stress is known to aggravate urticaria and stress reduction measures are very important in treating chronic urticaria.

Chronic urticaria can also be triggered by physical factors such as exposure to environmental heat (prickly heat), intense cold, sunlight, vibration or pressure on the skin (from tight clothing). Very rarely some people react to bath water, this is called “Aquagenic” Urticaria. Exercising after eating certain foods such as wheat, celery and shellfish might provoke delayed urticaria. Many people have very sensitive skin and any friction or rubbing will cause raised red lines to develop. This is called Dermatographism and indicates just how easily they can release histamine in their own skin. A good test for cold urticaria is to hold a block of ice against the skin for 5 minutes and see if an urticaria weal develops after the ice is removed.

Underlying thyroid diseases and autoimmune diseases such as Systemic Lupus and Rheumatoid Arthritis can provoke Chronic Urticaria or even Urticarial Vasculitis (a variant in which the lesions tend not to fluctuate but lead to skin discolouration). Urticarial Vasculitis may be associated with a fever, bone pains and joint swelling (Schnitzler’s Syndrome).

Occasionally an inherited deficiency of the C1 Esterase Inhibitor Enzyme leads to a non-itchy form of urticaria called Hereditary or Familial Angioedema. This condition affects mainly females in a family, is associated with sudden swelling of the face and neck which is not itchy but tends to be painful. These lesions usually last for 2 to 3 days and do not respond to antihistamine medication. Sufferers characteristically have low levels of the Complement C4 in their bloodstream and respond to medication called Danazol or Tranexamic acid which prevents attacks.

refs?

[psmith]

well, another wasted day of training. went into the gym, extremely cool outside, was wearing a jacket. came in, decided i was going to train back, as I start with lat pulldowns I start to break out, then I think everyone is watching me and it pushes me over the edge, so I have to leave my training once again! I seriously cannot continue like this!

[Warrior]

Anyway, that’s a brief description about the pain, and I was told that I have an allergic reaction to testosterone, rather cortisone that is based in Deca-Durabolin what is actually used to treat chronic Uticeria had caused this problem to get worse as now due to the length I have used this drug my body has become dependant on cortisone to help relieve the pain of the Uticeria, as I feel much better when I’m on a cycle, but as soon as I come off I have the most severe outbreaks everyday, most of the day, it has totally wrecked my life as I can’t do anything, (meetings, etc) without worrying about myself breaking out.

You need a new endocrinologist.

First, you can not become allergic to testosterone - it is a naturally occuring hormone that has flown through your body since you were a fetus. Being so, I don't see how you could be allergic to supraphysiological levels of testosterone either.

Second, cortisone is deffinitly not "based in Deca". One is an anabolic steroid and the other is a catabolic steroid - they would compete against each other. Testosterone and it's deriatives (like the 19-Nors; such as Nandrolone, or Deca) cross-over bind to gluco corticoids...

If you self administered Deca while recieving corticosteroid treatment from a doctor - that was a big mistake. If so, you need to tell them what you have taken...

Third - you have to be slowly weened off Corticoids to give your body the time to start producing it's own cortisol... it can be a slow process - but it's a mandatory one to make a successful transfer off the exogenous support.

Have you explored non-steroidal anti-inflamatory options with your doctor(s)? My first opinion of this whole thing: get a new doctor.

[perfectbeast2001]

I had utricaria when I came off last cycle. It lasted for about 2 months. It was worst at night when I would itch so bad I couldn'r sleep and I scratched my self raw on my legs. I did not at the time associate it with AS. Everything I read about it told me to look at diet, and stuff like shampoo or washing powder. In the end it went away and hasn't come back. I still don't know what caused it and nor did the doctor who to be honest wasn't very interested. I feel for you though mate because it drove me ****ing mad. Some nights i wanted to cut my legs off!

[psmith]

Sorry, I should have explained myself better earlier. I understand you can’t become allergic to testosterone, but one can be allergic to medicine (steroids). As far as Deca-Durabolin having cortisone in it may be incorrectly pronounced but could it increase cortisone levels in the body? Why I’m asking is that a person with chronic Uticeria shouldn’t administer any cortisone as it is such a powerful drug, once off normal antihistamines do not work any longer. What I can’t understand is that when I’m on a course of steroids, I can get away with training, I do break out a lot, but no where near as bad as when I come off steroids. And I have tried over 3 doctors in the UK and been to 2 doctors in South Africa and 1 professor who solely deal with dermatology. So I’m not sure where else to go with this, and I’m so scared that I start another course now that it aggravates it worse again, certain chemical properties in steroids could be causing the Uticeria, and well Professor Abu Baker believes it is solely due to the steroid use. Specially why it starts to ease, when I say ease doesn’t break out 20 times a day and more like 3 times and sometimes doesn’t cause the wheels to show but rather just the pain! Yet my body’s temperature is lower being off steroids due to a lower blood pressure level so that already helps as my body is cooler as not to set it off that much quicker also because the steroids stay so long in the body, maybe I’m getting relief once the steroids are starting to whine them self out of the system?

Sorry I might have twisted some of the things I have said, just wrote what I was feeling at the time.

Thanks very much for the posts; you have cleared some things up. I would like to give you estimate of how long I have been having this problem and its around 2 years now, maybe longer, I really cannot have this carry on for another year or so.

[psmith]

I had utricaria when I came off last cycle. It lasted for about 2 months. It was worst at night when I would itch so bad I couldn'r sleep and I scratched my self raw on my legs. I did not at the time associate it with AS. Everything I read about it told me to look at diet, and stuff like shampoo or washing powder. In the end it went away and hasn't come back. I still don't know what caused it and nor did the doctor who to be honest wasn't very interested. I feel for you though mate because it drove me ****ing mad. Some nights i wanted to cut my legs off!

heh, man you ripped ye, I don't wish this apon my worst enemy and ye, doctors don't reallly pay much intrest to this. i'v brought them so many articles i'v read on the internet and they just waver it off. I have heard though from some pro's and a steroid dealer that has been dealing for around 15 years that he has had people complain when using sustanon about itching, etc but they came fine after stopping the administration of the steroid, *shrugs*

[stupidhippo]

I didnt read the whole thing but if ur condition get worse during a cycle it might be due to AAS cortisol blocking action... cortisol which suppresses allergic/hyperreactive reactions..

[psmith]

No it gets worse after a cycle, see cortisone is so bad for a person with this condition, so maybe due to the AAS cortical blocking ability, once I come off my body’s natural functionality isn't strong enough and therefore the histamine is getting pumped out madly throughout the body

[stupidhippo]

is cortisol really bad for that condition.? can u referance that? too olazy to look it up.. isnt cortisol supposedly really high after a cycle?

[stupidhippo]

just read about it.. cortisol is used in therapy of urticaria also...

here a copy paste:
Glucocorticoids stabilize mast cell membranes and inhibit further histamine release. They also reduce the inflammatory effect of histamine and other mediators.
The efficacy of glucocorticoids in acute urticaria remains controversial. However, they are generally recommended in more severe and refractory cases.
In adults, 40-60 mg daily of prednisone for 5 days is a reasonable therapeutic regimen. In children, the treatment is 1 mg/kg/d for 5 days.
The efficacy of epinephrine in acute urticaria is controversial. If angioedema is present with urticaria, 0.3-0.5 mg of epinephrine should be administered subcutaneously. Remember that ACE-inhibitor–induced angioedema does not respond to epinephrine or any other therapy, since it is not an IgE-mediated process.
The use of methotrexate, colchicine, dapsone, indomethacin, and hydroxychloroquine may be effective in the management of vasculitic urticaria.

[psmith]

Yes now in my case the worst thing you can do is treat the Uticeria with cortisone as my body becomes dependant on it and requires higher and higher doses and the first day I stop taking it break out with wheels all over my body. The professor said to me in my case the worst thing I could do was take cortisone, now back to the main point of my quote was to find out what type of steroids I would be safe in using that wouldn't suppress or increase cortical levels in any way? Funnily enough it started easing a bit and then I took some Proviron and it broke out again. I’m not sure if there is some chemical property in these steroids I have used that my body is allergic to. I'm having a hard time researching exactly what properties are in steroids or even maybe the oil? something I know is triggering it and I don't believe its a food group as that only really is a problem in acute and not chronic conditions and I have tried just about every diet and stopped just about everything possible know to aggravate it, e.g.: flavourings, preservatives, colouring, tartrazine, msg, etc. and nothing has helped to take it away, yet just staying off steroids for a long period of time has helped the condition in a huge way.

The real reason for my article is not really to find a cure because not even the greatest specialist to this condition has a fix, he just states that is goes away after a few years and your bodies antibodies stop creating their own antibodies that are in essence destroying their own antibodies, if that makes any sense, but its pretty much the way diabetes is created as your bodies own immune system destroys the pancreatic cells.

Just maybe somebody other than me has had this problem due to steroid use, or not necessarily the steroid themselves but some sort of effect they have on my system. Specially if somebody has very allergic tendencies, as I have been allergic to milk when I was a kid and having that said some research said somewhere in ones life with this type of allergy will quite possibly develop some sort of Uticeria chronic or acute, the worst thing about this condition in a hot tropical climate like South Africa is that’s its always warm! Making it nearly impossible to even hop into your car without breaking out, luckily a cool air blowing against me and sometimes a cold shower cools my body down. It’s like I am always warm, others complain about the cold all the time and I’m standing their with my shirt off. Maybe this could even be a thyroid issue or even your liver? Thing is I don’t want to spend too much cash on these tests unless I have some sort of a direction to go in.

Thanks once again…

[stupidhippo]

[QUOTE=psmith]
The real reason for my article is not really to find a cure because not even the greatest specialist to this condition has a fix, he just states that is goes away after a few years and your bodies antibodies stop creating their own antibodies that are in essence destroying their own antibodies, if that makes any sense, but its pretty much the way diabetes is created as your bodies own immune system destroys the pancreatic cells.

Hehe... the bold sentence doesnt really make sense... it could be like this: your bodies lymphocytes stop producing antibodies that are in essence attacking the bodys own antigens.

But as far as your problem.... really dont have an idea what to do. the cortisol explanation makes sense this way u wrote about it. No point in keeping the cortisol dose up cause it has serious side-effects.. I think in your case the only thing u can do is try urself and keep looking for someone in a similar situation... its unlikely u will get a good answer around here. being that u have talked to several specialists in the matter... good luck ..

[cj1capp]

refs?

here is where i got that
http://www.allergy-clinic.co.uk/

[perfectbeast2001]

not ideal but if AS helps then stay on a low dose HRT. I would rather have the sides from the test than that damn itching back again.

[beachbum28]

Hey Bro... I don't know anything about what you have and I feel for ya. From what I get, it sounds more like a food allergy in the form of hives or rash. In this case...have you tried Lysine tabs? They will kick the shit out of herps and Hives. I used to get cold sores from stress but when I started Lysine they went away fast and stayed gone. Get the 1000 mg tabs, take two when you break out and then 1 or 2 tabs a day should keep it under control. My friend had hives really bad and I told him..now he's free from them going on 8 months! Let me know what happens if you decide to try it. No worries either...just an essential amino acid complex. Best of luck bro

[dbacs]

I have chronic urticaria also. I've had it for 7 years and it never goes away. Believe me it is torture.

I am currently on methylprednisone (cortisone). This is the only medicine that has ever worked for me. My hives are resistant to every possible medication on the planet. I go to one of the premiere immunoligists in the country, US, and he says that i have the worst case of hives he has ever seen and he travels the world.

So i've been searching for any possibility of relief. I have found studies that show stanozolol and danazol have provided some relieve for patients who benefit from cortisone only. I have tried to sway my doctor to prescribe some winstrol (stanozolol) for relief with no success. Now there is, supposedly, a dietary supplement called Mega-Zol that is supposed to work similar to winstrol. I may give it a go. I have tried winstrol before with some success, but could not afford more than 10 days worth. So i'm thinking i did not give it a long enough chance to kick in.

I actually find more relief by cycling my cortisone. I take about a week or two of a low dosage 4mg. Then i come off it for a couple days until the hives come back. This will allow your body to not be as reliant on cortisone, and is less likely that your adrenal glands will shut down. Also depending on the type of cortisone you use doctors will prescribe every other day usage. I do not think that cortisone, in your case, would cause the hives. That rarely ever happens. When you come off a cycle your prolactin increases also. Maybe look into that. I'm also doing this and use vitex agnus. This does help some. Take it at night, because prolactin is highest at night.

If you do not respond to any antihistamine it is most likely that your urticaria is autoimmune induced. Meaning that it is not an allergy to a substance you are ingesting, breathing in, etc. Make sure that you search for "autoimmune chronic urticaria" when looking for help. Try to get a doctor in a large hospital. Most of the local docs really have no clue as to helping with the disorder.

Oh yeah. Also it turns out that Whey and Egg proteins may be strengthening your immune system. Which means that these proteins could be kicking your hives into high gear for no apparent reason. I find that clean meats like, chicken, pork, or steak works best for me.

I am going to rush out right now and try the Lysine that was mentioned. I find that i am getting the best relief from creatine, lots of fluids, strength and endurance training, ALA, NAC and Wellbutrin SR. There is new evidence that dopamine agonists help autoimmune disorders, hence the Wellbutrin and vitex agnus is also a dopamine agonist.

Phew. A lot of info. I guess i'll keep you posted on the stanozolol and the lysine results. Good luck with your hives.

[dbacs]

I also just wanted to say that testosterone itself can modulate the immune system. If there is a medicine that works for the hives you should take it. But remember take it at the lowest possible dose. So start at the point where your cycle begins and slowly decrease until you start to get some hives. Then bump up the testosterone to where you didn't have the hives.

So heres what you have to ask yourself, "which one would i rather be on long term? test or cort?". Both are bad and have their side effects. To me test has less sides and can actually help the body, in low doses. BTW how old are you? I was 25 when i first started to get the hives. This is a common age for autoimmune problems, like hives.

[AnabolicBoy1981]

Hi I just wanted to make this post to see if anyone else has had the unfortunate problem of developing chronic Uticeria from steroid use. I have used steroids for a couple of years now and during the time I spent in London I developed this chronic Uticeria. It is the most painful experience you can imagine, where you whole body starts to burn like on fire and you get these wheels all over your body, mine luckily goes away after 15 minutes or so, but I have to get to cool air before it becomes unbearable.

Anyway, that’s a brief description about the pain, and I was told that I have an allergic reaction to testosterone, rather cortisone that is based in Deca-Durabolin what is actually used to treat chronic Uticeria had caused this problem to get worse as now due to the length I have used this drug my body has become dependant on cortisone to help relieve the pain of the Uticeria, as I feel much better when I’m on a cycle, but as soon as I come off I have the most severe outbreaks everyday, most of the day, it has totally wrecked my life as I can’t do anything, (meetings, etc) without worrying about myself breaking out.

Maybe somebody could share some light on this and help with some solutions to cure this problem I have as I can’t even gym anymore and I’m starting to get such depression as I can’t use gear again or train, when I do I suffer and I just can’t go through it anymore, SOMEBODY PLEASE HELP, I’ve tried every type of antihistamine, camomile teas, nettle teas, and nothing has removed this completely now I’m using the a very expensive antihistamine everyday during the day called Cestine, and at night Finnegan, but I’m draining during the day because of the sedative properties of the Finnegan and I would really like to stop having to take something to try eliminate it from breaking out?

HOLY CHRIST! NOT TO FLAME..BUT ....you gotta learn more about your steroids.

oh and find a new doctor. shes fired.

First off, deca durabolin is not based on cortisone! Cortisone is synthetic cortisol, thats it. Cortisone has anti-inflammatory properties, and is an adrenal hormone (like adrenelin), and has no androgenic actions in the body, nor anabolic actions ither(in fact its actually highly catabolic). The only reason it is classified a steroid is because its molecular structure is based on choloesterol. All steroid hormones are based on cholesterol. This has nothing to do with actions they exert on the cell. Thats why the steroids we all use here on this board are classified "anabolic/androgenic steroids". Got it?

Your problem: you cant have an allergic reaction to testosterone, but you can have an allergic reaction to the ESTER, (propionate, enanthate, cypionate, undeclynate, etc) or preperation. So we cannot rule that out.
However, i think your problem is cortisol.

The reason you are gettin issue when you come "off" is because anabolic steroids block cortisol receptors. When you come "off" this cortisol is built up and is one of the reasons(along with HPTA shutdown) that guys lose muscle after a cycle cuz it is catabolic and eats up muscle tissue. YOU on the other hand have this uticeria problem that actually causes burning and itching in the presence of elevated cortisol(strange since cortisol is anti-inflammatorry and itching/burning are inflmmatory actions), so you are doubly ****ed when you come "off" cycle. HOWEVER, cortisal is why guys take clen, in post cycle therapy, to block some of the cortisol!
So jump on some clen or albuteral post cycle and see if that helps. its worth a shot.

IF, your problem is allergic reactions to esters you may need to use only esterless steroids like test suspension and boldenone no ester. Or you may, through trial and error, be able to find esters that dont bug you.

but from what you guys say about uticeria, get some clen asap.

[dbacs]

As i've stated above i went out today and got some Lysine for myself. I have taken two doses, 1000mg, twice. So far my hives are very good right now. I actually don't have a single hive on my entire body. This is kind of freaking me out a little. I have never had a point in the past 7 years where i've been completely hive free. So i'm skeptical of what's going on.

But if this keeps up for more than 4 days then i would say we have a winner for Lysine.

I'm going to check into that Clen and L-Taurine. I would guess that the L-Taurine would be to increase vasodilation while on the Clen, plus liver support?

Oh yeah. Also search for articles of Chronic Urticaria and Anemia. I've seen some studies that show anemia can contribute to chronic urticaria. Today i also started a B vitamin supp and an iron supp. This could also be helping.

I also found a study today where Lysine has helped Rheumatoid Arthritis, another autoimmune disease. What happens is there is a virus that hangs around in the body and triggers an autoimmune reaction, causing the hives. The virus is harmless, but is deemed foreign to the body so the immune system attacks the body. Or something like that. I actually had Rheumatoid Arthritis when i was younger, and now the hives. So maybe this is a connection. Hmmm.

BTW, anyone, anywhere, at anytime in their life can develop autoimmune chronic urticaria. So don't rule out this possiblity. Just FYI.