hGH PROTEIN PEPTIDE FRAGMENT 177-191

[RoadToRecovery]

I was just wondering if anyone here has had experience with this stuff in regards to fat burning?

[RoadToRecovery]

bump

[dblock189]

bump im curious too

[Zelos]

i started 1 week ago , no results for the moment

[RoadToRecovery]

Damn... its never that easy i guess

[Zelos]

yes , should use for several months i think.

[RoadToRecovery]

wow... than it should be pricey huh?

[Zelos]

yeah exactly.
I think good diet + clen + T3 + tren will make better results and cheaper ...

[RoadToRecovery]

I heard t3 was dangerous shit

[Zelos]

I heard t3 was dangerous shit

if you respect the dose should be safe.
clen is dangerous too if you hyperdose it ( heart attack ).
So everything is dangerous if you extradose it , safe when you take reasonnable dose ....

[RoadToRecovery]

what ddo you consider a reasonable dose... i take 150mcg a day of clen

[Zelos]

you look huge , i think 120µg , 2 times day will be better.

[RoadToRecovery]

really?
Naah Im not that big... Only like 195lbs 16% BF....

But hey i just took my 150mcg... I take 90mcg later... see what thats like.

[Zelos]

on what i read , recommandation is a little under 1µg/lbs.
So for you should be less than 195µg/ 2 times/day , so 120-150µg should be safe.
Take 120µg/2 times days with some T3 , and you will reinforce the effect of both.
If you add Trenbolone , should be a detonator mix

[plzr8]

on what i read , recommandation is a little under 1µg/lbs.
So for you should be less than 195µg/ 2 times/day , so 120-150µg should be safe.
Take 120µg/2 times days with some T3 , and you will reinforce the effect of both.
If you add Trenbolone , should be a detonator mix

before anyone asks.... µg = mcg

[goose]

before anyone asks.... µg = mcg

Would you use ?

hGH PROTEIN PEPTIDE FRAGMENT 177-191

State why or not?

[plzr8]

Would you use ?

hGH PROTEIN PEPTIDE FRAGMENT 177-191

State why or not?

haven't considered it yet due to lack of research....guess only time will tell as there are several guys on this and other boards running it

[RoadToRecovery]

bump

[Zelos]

3 weeks on it , 0 results , nada ....

[RoadToRecovery]

wow that sucks

[Zelos]

yeah and this sh1t costs one arm !
i will never try this again , since it needs several months to have results.
I should have much better results with a cuting cycle !

[longhorn814]

the reason youre not having results is b/c your using the wrong fragment. You need to find frag Tyr 176-191, not 177-191 There are lots of people using the 176-191 frag and having great results. Im about to start some in a week too!!

[plzr8]

the reason youre not having results is b/c your using the wrong fragment. You need to find frag Tyr 176-191, not 177-191 There are lots of people using the 176-191 frag and having great results. Im about to start some in a week too!!

might also give it a run in a week or so....hearing some decent things

[Vader79]

the reason youre not having results is b/c your using the wrong fragment. You need to find frag Tyr 176-191, not 177-191 There are lots of people using the 176-191 frag and having great results. Im about to start some in a week too!!

So are you saying that Lion got it wrong and stocked a useless fraction in 177-191?

[RoadToRecovery]

Well i guess this is where it gets confusing

[longhorn814]

So are you saying that Lion got it wrong and stocked a useless fraction in 177-191?

Actually there were a lot of places selling the 177-191 frag and almost all people who tried experienced zero results. The Tyr 176-191 frag is a newer product on the market and so far people have been experiencing good results.

[Zelos]

mine is 176-191

[longhorn814]

DEVELOPMENT OF A HUMAN GROWTH HORMONE PEPTIDE ANALOGUE AOD9604 INTO AN ANTI-OBESITY DRUG.
Woei-Jia Jiang, Robert Gianello, Mark Heffernan, Esra Ogru, Roksan Libinaki and Frank Ng, from ***artment of Biochemistry and Molecular Biology, Monash University, Victoria 3800, Australia

Previous studies from our laboratory have identified that a carboxy-terminal fragment of the human growth hormone (hGH), hGH(177-191), is the lipolytic/anti-lipogenic domain of intact hGH [1]. By targeting the key enzymes involved in lipid metabolism, hGH(177-191) is able to increase lipolysis, and decrease lipogenesis in adipose tissue, resulting in reduction of body weight gain in obese rodent models.
In view of its significant clinical potential, the aim of our study is to develop the peptide into a drug for the treatment of human obesity. A series of peptide analogues of hGH(177-191) were designed, synthesized and studied for the structure-activity relationship. Among them, Tyr176-hGH(176-191), coded as AOD9604, was found to be one of the most active analogues and therefore selected as the drug candidate for further development [2]. With the extension on the amino terminus of hGH(177-191) by a single tyrosine residue, AOD9604 not only showed a 54% increase in the in vitro bioactivity but also demonstrate its in vivo bioactivity by reducing the body weight gain in the tested animals after chronic oral administration. Further studies by 2D-NMR indicated that the conformation of AOD9604 is relatively constrained and rigid, which may result in its good stability and therefore its oral bioavailability. Preclinical toxicology of AOD9604 was successfully completed with no unfavorable side effect observed and the Phase I human clinical trials are currently on-going.

This project is supported by Metabolic Pharmaceuticals Limited, Melbourne, Victoria 3142, Australia. (www. Metabolic.com.au)

[1] Ng, F., Natera, S., Jiang, W.-J. US Patent No. 5,869,452 (1999).
[2] Ng, F., Jiang, W.-J. International Patent Application PCT/AU98/00724. Published and proceeding.

[Vader79]

Now this is confusing. The thread starter specifically asked about 177-191, Zelios replied saying that he'd tried it (i assumed 177-191) and that so far it wasn't working. Then Longhorn explains to us that tyr176-191 is the superior fat burner in the sequence (according to published papers). Then Zelios says that actually he didn't use 177-191, he used try176-191, but nevertheless, it didn't work.

So it seems that Tyr 176-191 is superior to 177-191 in terms of lipolytic properties, although Zelios say's it doesn't work, but 177-191 is even worse?

[RoadToRecovery]

so then what is it? 177 or 176

[Zelos]

176-191 is 177-191 with tyrosine link at the beginning of the chain.
I used 176-191 because i read before that 177-191 was a waste of time and money.
176-191 is the same for me , a pure waste of money !

[longhorn814]

176-191 is 177-191 with tyrosine link at the beginning of the chain.
I used 176-191 because i read before that 177-191 was a waste of time and money.
176-191 is the same for me , a pure waste of money !

well there is only one place that I know of that has Tyr 176-191 and everybody that has posted reviews on it has had great results. Ive got some arriving today and will be starting tomorrow.

[plzr8]

well there is only one place that I know of that has Tyr 176-191 and everybody that has posted reviews on it has had great results. Ive got some arriving today and will be starting tomorrow.

ditto

[Zelos]

well there is only one place that I know of that has Tyr 176-191 and everybody that has posted reviews on it has had great results. Ive got some arriving today and will be starting tomorrow.

yeah good , keep us updated .

[longhorn814]

started 300mcg of the Tyr 176-191 frag this morning

[Zelos]

longhorn , the vials you received was 2mg or 10mg ?
How did you reconstitute them ?

Thanks.

[longhorn814]

longhorn , the vials you received was 2mg or 10mg ?
How did you reconstitute them ?

Thanks.

I received 5mg vials of the frag. Just reconstituted with BW.

[Zelos]

I received 5mg vials of the frag. Just reconstituted with BW.

Can i contact you by mp ?

[Garbanzo Dude]

bump for any new info

[Jeff1]

I got some over a year ago and have yet to crack them open..
I think im just going to stick to my Blues =)