
Originally Posted by
daem
Personally, I feel with front loading that you need to "bite the bullet" so to speak.
The most important thing is getting the body into a steady, predictable state by being consistent with injections / frequency.
While it takes longer to "kick" when you start if you don't frontload, you are less likely to experience any rapid buildup or flux with estradiol in your blood.
If you have been taking an anti-estrogen like arimidex or letrozole, you won't have to worry but you may still experience some acne, bloat, or oily skin with the frontload.
I would hit all 1g at once, split up into 2ml / injection on Day 1. The real debate is whether or not you should hit the next working dosage on Day 4 or 5, or skip that injection and wait until 1 week after your frontload dosage.
I've tried it both ways, and I prefer hitting my working dosage (in your case, 250mg) on Day 4 to get the cycle into high gear ASAP.